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June 1, 1999

Falling asleep at the wheel: Motor vehicle mishaps in persons taking pramipexole and ropinirole

June 1, 1999 issue
52 (9) 1908

Abstract

Article abstract The authors report a new side effect of the dopamine agonists pramipexole and ropinirole: sudden irresistible attacks of sleep. Eight PD patients taking pramipexole and one taking ropinirole fell asleep while driving, causing accidents. Five experienced no warning before falling asleep. The attacks ceased when the drugs were stopped. Neurologists who prescribe these drugs and patients who take them should be aware of this possible side effect.

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Information & Authors

Information

Published In

Neurology®
Volume 52Number 9June 1, 1999
Pages: 1908
PubMed: 10371546

Publication History

Received: December 22, 1998
Accepted: February 26, 1999
Published online: June 1, 1999
Published in print: June 1, 1999

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Authors

Affiliations & Disclosures

S. Frucht, MD
From the Columbia-Presbyterian Medical Center (Drs. FruchtGreene, and Fahn) and Beth Israel Medical Center (Dr. Rogers), New York, NY; and the Long Island Jewish Medical Center (Dr. Gordon), New Hyde Park, NY.
J.D. Rogers, MD
From the Columbia-Presbyterian Medical Center (Drs. FruchtGreene, and Fahn) and Beth Israel Medical Center (Dr. Rogers), New York, NY; and the Long Island Jewish Medical Center (Dr. Gordon), New Hyde Park, NY.
P.E. Greene, MD
From the Columbia-Presbyterian Medical Center (Drs. FruchtGreene, and Fahn) and Beth Israel Medical Center (Dr. Rogers), New York, NY; and the Long Island Jewish Medical Center (Dr. Gordon), New Hyde Park, NY.
M.F. Gordon, MD
From the Columbia-Presbyterian Medical Center (Drs. FruchtGreene, and Fahn) and Beth Israel Medical Center (Dr. Rogers), New York, NY; and the Long Island Jewish Medical Center (Dr. Gordon), New Hyde Park, NY.
S. Fahn, MD
From the Columbia-Presbyterian Medical Center (Drs. FruchtGreene, and Fahn) and Beth Israel Medical Center (Dr. Rogers), New York, NY; and the Long Island Jewish Medical Center (Dr. Gordon), New Hyde Park, NY.

Notes

Address correspondence and reprint requests to Dr. S. Frucht, The Neurological Institute, 710 West 168th Street, New York, NY 10032.

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