Safety and efficacy of pallidal or subthalamic nucleus stimulation in advanced PD
This article has been corrected.
VIEW CORRECTION
Abstract
The authors retrospectively compared 1-year results of bilateral deep brain stimulation (DBS) of the subthalamic nucleus (STN; n = 16) and internal pallidum (GPi) (n = 11) in advanced PD and found about equal improvements in “off” period motor symptoms, dyskinesias, and fluctuations. STN stimulation reduced medication requirements by 65% and required significantly less electrical power. These advantages contrasted with a need for more intensive postoperative monitoring and a higher incidence of adverse events related to levodopa withdrawal.
Get full access to this article
View all available purchase options and get full access to this article.
References
1.
Burchiel KJ, Anderson VC, Favre J, Hammerstad JP. Comparison of pallidal and subthalamic nucleus deep brain stimulation for advanced Parkinson’s disease: results of a randomized, blinded pilot study. Neurosurgery . 1999; 45: 1375–1382.
2.
Krack P, Pollak P, Limousin P, et al. Subthalamic nucleus or internal pallidum stimulation in young onset Parkinson’s disease. Brain . 1998; 121: 451–457.
3.
DeLong MR. Primate models of movement disorders of basal ganglia origin. Trends Neurosci . 1990; 13: 281–285.
4.
Krack P, Pollak P, Limousin P, et al. Opposite motor effects of pallidal stimulation in Parkinson’s disease. Ann Neurol . 1998; 43: 180–192.
5.
Bejjani BP, Damier P, Arnulf I, et al. Deep brain stimulation in Parkinson’s disease: opposite effects of stimulation in the pallidum. Mov Disord . 1998; 13: 969–970.
6.
Tronnier VM, Fogel W, Kronenbuerger M, Steinvorth S. Pallidal stimulation: an alternative to pallidotomy? J Neurosurg . 1997; 87: 700–705.
7.
Volkmann J, Sturm V, Weiss P, et al. Bilateral high-frequency stimulation of the internal globus pallidus in advanced Parkinson’s disease. Ann Neurol . 1998; 44: 953–961.
8.
Bejjani BP, Dormont D, Pidoux B, et al. Bilateral subthalamic stimulation for Parkinson’s disease by using three-dimensional stereotactic magnetic resonance imaging and electrophysiological guidance. J Neurosurg . 2000; 92: 615–625.
9.
Moro E, Scerrati M, Romito LM, et al. Chronic subthalamic nucleus stimulation reduces medication requirements in Parkinson’s disease. Neurology . 1999; 53: 85–90.
10.
Houeto JL, Damier P, Bejjani P, et al. Subthalamic stimulation in Parkinson disease: A multidisciplinary approach. Arch Neurol . 2000; 57: 461–465.
Information & Authors
Information
Published In
Copyright
© 2001.
Publication History
Received: July 24, 2000
Accepted: November 8, 2000
Published online: February 27, 2001
Published in print: February 27, 2001
Authors
Metrics & Citations
Metrics
Citations
Download Citations
If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Select your manager software from the list below and click Download.
Cited By
- Does Temporary Externalization of Electrodes After Deep Brain Stimulation Surgery Result in a Higher Risk of Infection?, Neuromodulation: Technology at the Neural Interface, (2023).https://doi.org/10.1016/j.neurom.2023.08.004
- Participant perceptions of changes in psychosocial domains following participation in an adaptive deep brain stimulation trial, Brain Stimulation, 16, 4, (990-998), (2023).https://doi.org/10.1016/j.brs.2023.06.007
- Stimolazione cerebrale e malattia di Parkinson, EMC - Neurologia, 23, 2, (1-16), (2023).https://doi.org/10.1016/S1634-7072(23)47685-4
- Deep Brain Stimulation in the Subthalamic Nucleus Can Improve Skilled Forelimb Movements and Retune Dynamics of Striatal Networks in a Rat Stroke Model, International Journal of Molecular Sciences, 23, 24, (15862), (2022).https://doi.org/10.3390/ijms232415862
- Peri-lead edema and local field potential correlation in post-surgery subthalamic nucleus deep brain stimulation patients, Frontiers in Human Neuroscience, 16, (2022).https://doi.org/10.3389/fnhum.2022.950434
- Unilateral GPi-DBS Improves Ipsilateral and Axial Motor Symptoms in Parkinson’s Disease as Evidenced by a Brain Perfusion Single Photon Emission Computed Tomography Study, Frontiers in Human Neuroscience, 16, (2022).https://doi.org/10.3389/fnhum.2022.888701
- Behavioral disturbances in Parkinson's disease, Dialogues in Clinical Neuroscience, 6, 3, (323-332), (2022).https://doi.org/10.31887/DCNS.2004.6.3/kanderson
- Elektrische Stimulation tiefer Hirnstrukturen: Auswirkungen auf das Sprechen, Sprache · Stimme · Gehör, 46, 04, (181-193), (2022).https://doi.org/10.1055/a-1941-3588
- The risk factors of intracerebral hemorrhage in deep brain stimulation: does target matter?, Acta Neurochirurgica, 164, 2, (587-598), (2022).https://doi.org/10.1007/s00701-021-04977-y
- Deep Brain Stimulation, Koht, Sloan, Toleikis's Monitoring the Nervous System for Anesthesiologists and Other Health Care Professionals, (73-90), (2022).https://doi.org/10.1007/978-3-031-09719-5_5
- See more
Loading...
View Options
Get Access
Login options
Check if you have access through your login credentials or your institution to get full access on this article.
Personal login Institutional LoginPurchase Options
Purchase this article to get full access to it.