Lyme disease associated with Alzheimer's disease

Curr Microbiol. 2006 Apr;52(4):330-2. doi: 10.1007/s00284-005-0454-7. Epub 2006 Mar 9.

Abstract

This case report discusses a patient with co-occurring neuroborreliosis and Alzheimer's disease (AD). Although no claim is made for causality nor is there objective evidence that spirochetes are involved in AD, co-infection may exacerbate the symptoms of either neuroborreliosis or AD. Much is to be learned about the role of spirochetes in degenerative central nervous system disease.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Alzheimer Disease / complications
  • Anti-Bacterial Agents / therapeutic use
  • Borrelia burgdorferi / classification
  • Borrelia burgdorferi / genetics
  • Brain / microbiology
  • Brain / pathology*
  • DNA, Bacterial / analysis
  • Doxycycline / therapeutic use
  • Female
  • Humans
  • Lyme Disease / complications*
  • Lyme Disease / drug therapy
  • Lyme Disease / microbiology

Substances

  • Anti-Bacterial Agents
  • DNA, Bacterial
  • Doxycycline