Abstract
Our results show that impairment of the gastrointestinal tracts in human immunodeficiency virus (HIV)-positive patients is present in the early phases of HIV disease. This impairment is associated with alterations in gut microbiota and intestinal inflammatory parameters. These findings support the hypothesis that alterations at the gastrointestinal-tract level are a key factor in HIV pathogenesis.
MeSH terms
- Feces / chemistry
- Feces / microbiology
- Gastrointestinal Tract / immunology
- Gastrointestinal Tract / microbiology*
- Gastrointestinal Tract / pathology*
- HIV / physiology
- HIV Infections / complications*
- Humans
- Inflammation / immunology
- Inflammation / microbiology
- Inflammation / pathology*
- Intestinal Mucosa / immunology
- Intestinal Mucosa / pathology*
- Intestinal Mucosa / physiopathology*
- Leukocyte L1 Antigen Complex / analysis
Substances
- Leukocyte L1 Antigen Complex