Overview
In mammal species, and in many other species, most cells show a continuous turnover that is more or less rapid depending on cell types. Some cell types, i.e., most neurons, on the contrary, are never renewed, and the same cells present in the young still exist in the individual of any subsequent age. Here, only the subject of aging for these cells, defined perennial cells, is discussed. For the aging of non-perennial cells or for the mechanisms of aging in general, the entry Aging mechanisms should be looked up.
There are two completely different interpretations of the mechanisms of aging for perennial cells: the nonadaptive and the adaptive aging theories.
Mechanisms of Aging for Perennial Cells According to Nonadaptive (Non-programmed) Aging Theories
For these theories aging is due to the progressive accumulation of various damages that are insufficiently...
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Ferrara, N., Komici, K., Corbi, G. (2019). Aging for Perennial Cells. In: Gu, D., Dupre, M. (eds) Encyclopedia of Gerontology and Population Aging. Springer, Cham. https://doi.org/10.1007/978-3-319-69892-2_30-1
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DOI: https://doi.org/10.1007/978-3-319-69892-2_30-1
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