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DOI: 10.1055/a-1314-9373
SARS-CoV-2-Diagnostik – was ist wirklich sinnvoll?
SARS-CoV-2 Diagnostic – What is Really Sensible?Zusammenfassung
Den Goldstandard zur Diagnose einer Infektion mit SARS-CoV-2 stellt aktuell (Stand November 2020) die PCR-Untersuchung dar. Diese ist jedoch vor allem zeitintensiv. In Zukunft könnten sog. Antigentests schnell und patientennah als Point-of-Care-Methode durchgeführt werden, um die Diagnosestellung einer SARS-CoV-2 Infektion zu erleichtern. Veränderungen serologischer Biomarker (wie D-Dimere, Troponin T, CRP) können helfen, Patienten mit einem Risiko für einen schweren COVID-19-Verlauf zu identifizieren. Ein routinemäßiges Screening-CT-Thorax zur Identifizierung einer COVID-19-Pneumonie wird derzeit von den meisten radiologischen Gesellschaften nicht empfohlen. Dennoch nimmt die Zahl der durchgeführten CT-Untersuchungen kontinuierlich zu, und die radiologische Diagnostik nimmt bei an COVID-19 erkrankten Patienten mit pulmonalen Symptomen einen immer wichtigeren Stellenwert in der klinischen Erfassung der Schwere der Lungenbeteiligung ein.
Abstract
The PCR-test for SARS-CoV-2 represents the state of the art in diagnosing COVID-19 disease as at November 2020. However, above all this is time-consuming. In future, so-called antigen tests could be carried out quickly and as a point-of-care method to facilitate the diagnosis of COVID-19. Changes in serological biomarkers (such as D-dimers, troponin T, CRP) can help to identify patients at risk for a severe COVID-19 course. A routine screening CT thorax to identify COVID-19 pneumonia is currently not recommended by most radiological societies. However, the number of CT examinations is increasing steadily and radiological diagnosis in COVID-19 patients with pulmonary symptoms is becoming more and more important.
Die PCR-Untersuchung auf SARS-CoV-2 stellt aktuell (Stand November 2020) den Goldstandard bei der Diagnosestellung einer COVID-19-Erkrankung dar.
Aufgrund der kürzeren Testlaufzeiten und einfacheren Verwendung werden Antigentests in Zukunft an Bedeutung gewinnen.
Eine rasche Diagnose der Infektion hilft, Infektionsketten zu durchbrechen und den Patienten eine Therapieoption anbieten zu können.
Die radiologische Untersuchung beschränkt sich meist auf die Computertomografie (CT) des Thorax. Hier können sich bereits früh Zeichen einer COVID-19-Pneumonie zeigen. Zudem kann die CT helfen, den Schweregrad der Erkrankung abzuschätzen. Ein routinemäßiges Screening-CT-Thorax zur Identifizierung einer COVID-19-Pneumonie wird derzeit von den meisten radiologischen Gesellschaften nicht empfohlen [1].
Publication History
Article published online:
21 January 2021
© 2021. Thieme. All rights reserved.
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