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Neuroscience
Exploring the origins of excitatory and inhibitory neuronal tuning in the postsubiculum
Brain cells can be broadly divided into two categories: inhibitory and excitatory neurons. Excitatory neurons are cells that support the generation of electrical impulses in postsynaptic neurons, thus prompting the activation ...
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Oncology & Cancer
Regulating cholesterol levels might be the key to improving cancer treatment
A team of researchers from Aarhus University has made a remarkable discovery that could improve cancer treatment and the treatment of a number of other illnesses. Their research is published in the journal Nature Communications.
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Medical research news
Patients diagnosed with cancer in prison more likely to die from the disease, research shows
Cancer patients diagnosed in English prisons do not receive the same level of curative treatment as those in the general population, meaning they are at increased risk of death.
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Cranberry extracts could boost microbiota and counter cardiometabolic diseases
Cranberry extracts appear to improve intestinal microbiota and help prevent chronic diseases such as diabetes and cardiovascular diseases. A recent study by Université Laval and the Institute of Nutrition and Functional ...
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Evidence-based integrated approaches provide new opportunities to improve complex pain management
Complex Regional Pain Syndrome (CRPS) is a chronic and debilitating pain disorder, typically considered lifelong with limited treatment options. Now, new research finds that early detection and effective treatment can lead ...
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Tsetse fly protein provides anticoagulant with its own on-off switch
Researchers at the University of Sydney and University of Geneva have developed a new anticoagulant, whose anticlotting action can be rapidly stopped "on demand." The result could lead to new surgical and post-operative drugs ...
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Does obesity really increase your risk of dementia?
Many dementia charities advise people to maintain a healthy weight to reduce their risk of dementia. But some studies have suggested that obesity might actually protect against dementia. What does the science say?
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Smoking and alcohol leading cause of surge in cancer deaths and cases in Asia, global study finds
A large new global study published in The Lancet Regional Health—Southeast Asia reveals that cancer-related deaths rose to 5.6 million in 2019 from 2.8 million in 1999 in Asia, attributing the surge mainly to smoking and ...
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What goal-directed learning is and why it's important for adolescents to learn from their actions
Imagine you're at a carnival and want to win a big stuffed toy. You play different games and, if successful, collect tickets. But it's not the tickets you care about, it's the big toy they'll buy.
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Medication-assisted treatment, along with group therapy, found to improve inhibitory control in heroin addiction
In line with their previous work, researchers from the Icahn School of Medicine at Mount Sinai showed that individuals with heroin use disorder have lower activity in the anterior and dorsolateral PFC when performing an inhibitory ...
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Study identifies immunity threshold for protection against COVID-19 in children
As COVID-19 becomes endemic, an important group of people who continue to require vaccination is future birth cohorts of children. Yet, in the face of everchanging variants, as well as the waning of antibodies with time after ...
1 hour ago
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Researchers target neurogenesis in new approach to treat Parkinson's disease
Researchers at the University of Toronto have found a way to better control the preclinical generation of key neurons depleted in Parkinson's disease, pointing toward a new approach for a disease with no cure and few effective ...
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Study introduces improved way to grow cells that give rise to kidney's filtration system
In a study published in Cell Stem Cell, USC scientists report significant progress in cultivating nephron progenitor cells (NPCs), the cells destined to form the kidney's filtration system, the nephrons. NPCs hold immense ...
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Study finds some people have a uniquely human gene that enhances immune function
University at Buffalo researchers have found that the active form of a gene promotes a broad range of protective traits. The gene is found in 75% of the population and is known to protect against neurodegeneration. Now, UB ...
1 hour ago
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Neuroscientists find integrity of white brain matter in superagers does not deteriorate, explains sharp memory
A team of neuroscientists from Universidad Politécnica de Madrid and Queen Sofia Foundation Alzheimer Center, both in Spain, has found that so-called superagers maintain memory as they grow older because they do not experience ...
Study highlights importance of early interventions to combat HIV
A study has compared the development of HIV reservoirs—locations in the body where the virus persists in a latent state—between patients who receive either early or late medical interventions. The findings highlight the ...
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Targeting protein interactions may boost antitumor immunity in breast cancer
A multi-institutional team of investigators has discovered that targeting a specific protein interaction within immunosuppressive breast cancer cells may increase antitumor immune responses in otherwise difficult to treat ...
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New drug candidate reverses obesity in mice
Researchers at Karolinska Institutet may have found a new way to treat obesity and related disorders by targeting the cells' mitochondria. A study published in Nature Metabolism shows that a specific class of drugs that block ...
2 hours ago
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A better COVID treatment for the immunocompromised? Researchers create a non-toxic potential alternative to Paxlovid
A combination of two antiviral compounds may be a promising alternative to Paxlovid when treating COVID-19 in immunocompromised patients, according to Karen S. Anderson, Ph.D., professor of pharmacology and of molecular biophysics ...
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Researchers identify gene linked to development of fatty liver disease
New research from the University of Aberdeen could lead to the development of medication for disease that affects 1 in 4 people worldwide but is currently untreatable.
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