Asymptomatic SARS-CoV-2 infections in pregnant patients in an Italian city during the complete lockdown

J Med Virol. 2021 Mar;93(3):1758-1760. doi: 10.1002/jmv.26458. Epub 2020 Sep 29.

Abstract

Data from both New York and London report a high prevalence of the asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pregnant patients admitted for delivery, raising questions on the possible correlated dangers (ie, contacts with healthcare workers; the possible creation of an intrahospital outbreak at birth; and conflicting evidence on vertical transmission). For this study, results from SARS-CoV-2 screening via nasopharyngeal swab from maternity wards of the four hospitals of Genoa, Italy, were collected during a month of complete lockdown from 1 April to 30 April 2020. Out of 333 tested women, only 9 were symptomatic. Only one symptomatic patient (0.3%) and six asymptomatic ones (1.8%) tested positive. Out of the six positive asymptomatic patients, five were from the most disadvantaged neighborhood of the city (assessed by postal code). In conclusion, even if Italy was badly affected by coronavirus disease 2019 in the studied month, the reported prevalence of SARS-CoV-2 infections in asymptomatic pregnant patients at term was lower than the ones reported in the literature.

Keywords: COVID-19 and pregnancy; SARS-CoV-2; asymptomatic COVID-19; maternal leave policies.

MeSH terms

  • Adult
  • Asymptomatic Infections / epidemiology*
  • COVID-19 / epidemiology*
  • COVID-19 / virology
  • Communicable Disease Control / methods
  • Disease Outbreaks / statistics & numerical data
  • Female
  • Health Personnel
  • Hospitalization / statistics & numerical data
  • Humans
  • Infectious Disease Transmission, Vertical / statistics & numerical data
  • Italy / epidemiology
  • London / epidemiology
  • Mass Screening / methods
  • New York / epidemiology
  • Pregnancy
  • Pregnancy Complications, Infectious / epidemiology*
  • Pregnancy Complications, Infectious / virology*
  • Prevalence
  • SARS-CoV-2 / pathogenicity