Abstract
We investigated a multi-family cluster of 22 cases in Jixi, where pre-symptomatic and asymptomatic transmission resulted in at least 41% of household infections of SARS-CoV-2. Our study illustrates the challenge of controlling COVID-19 due to the presence of asymptomatic and pre-symptomatic transmission even when extensive testing and contact tracing are conducted.
Keywords: Asymptomatic transmission; COVID-19; cluster; contact tracing; household close contact; pre-symptomatic transmission.
MeSH terms
- Adult
- Asymptomatic Diseases
- COVID-19 / diagnosis
- COVID-19 / epidemiology*
- COVID-19 / transmission*
- COVID-19 / virology
- COVID-19 Testing / methods
- Child
- China / epidemiology
- Contact Tracing / statistics & numerical data*
- Family
- Female
- Humans
- Male
- Pandemics*
- Public Health
- Quarantine / organization & administration
- Reverse Transcriptase Polymerase Chain Reaction
- SARS-CoV-2 / genetics*
- SARS-CoV-2 / isolation & purification
- Severity of Illness Index
- Surveys and Questionnaires
Grants and funding
This work was supported by Emergency Program for COVID-19 Prevention and Control of Guangdong Province: [Grant Number 2020KZDZX1226]; Emergency Response Program of Peng Cheng Laboratory: [Grant Number PCLERP001].