• Issue
    Volume 85, Issue 12
    2641-2890
    December 2019
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ISSUE INFORMATION

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Issue Information
  • Pages: 2641-2642
  • First Published: 12 January 2020

ISSUE HIGHLIGHTS

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Issue highlights
  • Pages: 2643-2644
  • First Published: 12 January 2020

EDITORIAL

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Goodbye to all that
Adam Cohen, 
  • Pages: 2645-2648
  • First Published: 12 December 2019

COMMENTARY

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Vaccine safety: An evolving evidence-based science
Bruce M. McClenathan,  Kathryn M. Edwards, 
  • Pages: 2649-2651
  • First Published: 02 August 2019

SYSTEMATIC REVIEW AND META-ANALYSIS

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A systematic review of patient-reported outcomes associated with the use of direct-acting oral anticoagulants
Saima Kishvar Afzal,  Syed Shahzad Hasan,  Zaheer Ud-Din Babar, 
  • Pages: 2652-2667
  • First Published: 11 May 2019
Free Access

Pharmacist services in nursing homes: A systematic review and meta-analysis
Shaun Wen Huey Lee,  Vivienne Sook Li Mak,  Yee Woon Tang, 
  • Pages: 2668-2688
  • First Published: 29 August 2019

REVIEWS

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New drugs approved for acute myeloid leukaemia in 2018
Selin Kucukyurt,  Ahmet Emre Eskazan, 
  • Pages: 2689-2693
  • First Published: 30 August 2019
Free Access

Immune-mediated adverse reactions to vaccines
Cosby A. Stone Jr,  Christine R.F. Rukasin,  Thomas M. Beachkofsky,  Elizabeth J. Phillips, 
  • Pages: 2694-2706
  • First Published: 31 August 2019
Free Access

A review of the prescribing trend of thiazide-type and thiazide-like diuretics in hypertension: A UK perspective
Ryan J. McNally,  Franca Morselli,  Bushra Farukh,  Philip J. Chowienczyk,  Luca Faconti, 
  • Pages: 2707-2713
  • First Published: 31 August 2019

ORIGINAL ARTICLES

Open Access

Polyethylene glycol loxenatide (PEX168) in subjects with renal impairment: A pharmacokinetic study
Jianwen Wang,  Jie Huang,  Wei Li,  Shiqi Tang,  Jian Sun,  Xianming Zhang,  Jun Liu,  Bin Yi,  Jishi Liu,  Xingfei Zhang,  Qian Yang,  Xiaoyan Yang,  Shuang Yang,  Guoping Yang,  Hao Zhang, 
  • Pages: 2714-2720
  • First Published: 08 August 2019
Open Access

Population pharmacokinetic modelling and simulation of fremanezumab in healthy subjects and patients with migraine
Jill B. Fiedler-Kelly,  Orit Cohen-Barak,  Denise N. Morris,  Elizabeth Ludwig,  Michele Rasamoelisolo,  Honglue Shen,  Micha Levi, 
  • Pages: 2721-2733
  • First Published: 16 August 2019
Free Access

Longitudinal exposure of English primary care patients to pharmacogenomic drugs: An analysis to inform design of pre-emptive pharmacogenomic testing
James E. Kimpton,  Iain M. Carey,  Christopher J.D. Threapleton,  Alexandra Robinson,  Tess Harris,  Derek G. Cook,  Stephen DeWilde,  Emma H. Baker, 
  • Pages: 2734-2746
  • First Published: 27 August 2019
Free Access

CD4+ count-dependent concentration–effect relationship of rituximab in rheumatoid arthritis
Amina Bensalem,  Denis Mulleman,  Gilles Thibault,  Nicolas Azzopardi,  Philippe Goupille,  Gilles Paintaud,  David Ternant, 
  • Pages: 2747-2758
  • First Published: 27 August 2019
Free Access

Pharmacokinetic–pharmacodynamic (dipeptidyl peptidase-4 inhibition) model to support dose rationale in diabetes patients, including those with renal impairment, for once-weekly administered omarigliptin
Lokesh Jain,  Anne S.Y. Chain,  Daniel A. Tatosian,  Jeremy Hing,  Julie A. Passarell,  Eunkyung A. Kauh,  Eseng Lai, 
  • Pages: 2759-2771
  • First Published: 27 August 2019
Free Access

Is the use of metformin in patients undergoing dialysis hazardous for life? A systematic review of the safety of metformin in patients undergoing dialysis
Christina Abdel Shaheed,  Jane E. Carland,  Garry G. Graham,  Sophie L. Stocker,  Greg Smith,  Mark Hicks,  Kenneth M. Williams,  Timothy Furlong,  Peter Macdonald,  Jerry R. Greenfield,  Felicity C. Smith,  Gina Chowdhury,  Richard O. Day, 
  • Pages: 2772-2783
  • First Published: 31 August 2019
Free Access

Impact of a targeted monitoring on data-quality and data-management workload of randomized controlled trials: A prospective comparative study
Claire Fougerou-Leurent,  Bruno Laviolle,  Christelle Tual,  Valérie Visseiche,  Aurélie Veislinger,  Hélène Danjou,  Amélie Martin,  Valérie Turmel,  Alain Renault,  Eric Bellissant, 
  • Pages: 2784-2792
  • First Published: 31 August 2019
Free Access

Toward a robust tool for pharmacokinetic-based personalization of treatment with tacrolimus in solid organ transplantation: A model-based meta-analysis approach
Tom M. Nanga,  Thao T.P. Doan,  Pierre Marquet,  Flora T. Musuamba, 
  • Pages: 2793-2823
  • First Published: 31 August 2019
Free Access

Population pharmacokinetics of sildenafil in extremely premature infants
Daniel Gonzalez,  Matthew M. Laughon,  P. Brian Smith,  Shufan Ge,  Namasivayam Ambalavanan,  Andrew Atz,  Gregory M. Sokol,  Chi D. Hornik,  Dan Stewart,  Gratias Mundakel,  Brenda B. Poindexter,  Roger Gaedigk,  Mary Mills,  Michael Cohen-Wolkowiez,  Karen Martz,  Christoph P. Hornik,  on behalf of the Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee , 
  • Pages: 2824-2837
  • First Published: 02 September 2019
Free Access

Hospitalization as an opportunity to correct errors in anticoagulant treatment in patients with atrial fibrillation
Yoel Angel,  David Zeltser,  Shlomo Berliner,  Merav Ingbir,  Itzhak Shapira,  Shani Shenhar-Tsarfaty,  Ori Rogowski, 
  • Pages: 2838-2847
  • First Published: 04 September 2019
Free Access

Maternal use of drugs and preeclampsia
Heidi Sahlman,  Marjaana Koponen,  Hani El-Nezami,  Kirsi Vähäkangas,  Leea Keski-Nisula, 
  • Pages: 2848-2855
  • First Published: 05 November 2019
Free Access

The safety of amoxicillin and clavulanic acid use during the first trimester of pregnancy
Sharon Daniel,  Maya Doron,  Boris Fishman,  Gideon Koren,  Eitan Lunenfeld,  Amalia Levy, 
  • Pages: 2856-2863
  • First Published: 05 September 2019
Open Access

Physiologically based pharmacokinetic evaluation of cefuroxime in perioperative antibiotic prophylaxis
Christer Rimmler,  Christian Lanckohr,  Ceren Akamp,  Dagmar Horn,  Manfred Fobker,  Karsten Wiebe,  Bassam Redwan,  Bjoern Ellger,  Robin Koeck,  Georg Hempel, 
  • Pages: 2864-2877
  • First Published: 05 September 2019
Open Access

A novel direct method to determine adherence to atorvastatin therapy in patients with coronary heart disease
Oscar Kristiansen,  Nils T. Vethe,  Morten W. Fagerland,  Stein Bergan,  John Munkhaugen,  Einar Husebye, 
  • Pages: 2878-2885
  • First Published: 08 September 2019

SHORT REPORT

Open Access

Intravenous flucloxacillin treatment is associated with a high incidence of hypokalaemia
Charlotte D.C.C. van der Heijden,  Marleen L. Duizer,  Hanneke W.H.A. Fleuren,  Bart A. Veldman,  Tom Sprong,  Anton T.S.M. Dofferhoff,  Cornelis Kramers, 
  • Pages: 2886-2890
  • First Published: 26 April 2019