Abstract
Age-related cardiovascular pathologic changes are inevitable and cardiovascular diseases are common in many older patients. Thus, in order to effectively treat geriatric patients, anesthesiologists should be able to recognize the contributions of both normal aging and overt disease to decrease cardiovascular reserve as well as understand the impact of anesthesia on cardiovascular homeostasis in the elderly.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Suggested Reading
Alexander KP, Newby LK, et al. Acute coronary care in the elderly, part II: ST-segment-elevation myocardial infarction: a scientific statement for healthcare professionals from the American Heart Association Council on Clinical Cardiology: in collaboration with the Society of Geriatric Cardiology. Circulation. 2007; 115(19): 2570–89.
Alexander KP, Newby LK, et al. Acute coronary care in the elderly, part I: Non-ST-segment-elevation acute coronary syndromes: a scientific statement for healthcare professionals from the American Heart Association Council on Clinical Cardiology: in collaboration with the Society of Geriatric Cardiology. Circulation. 2007; 115(19): 2549–69.
Andrawes WF, Bussy C, et al. Prevention of cardiovascular events in elderly people. Drugs Aging. 2005; 22(10): 859–76.
Barnett S, Jankowski C, et al. A Geriatric Anesthesiology Curriculum. S. f. A. o. G. Anesthesia. 2010.
Cruden NL, Harding SA, et al. Previous coronary stent implantation and cardiac events in patients undergoing noncardiac surgery. Circ Cardiovasc Interv. 2010; 3(3): 236–42.
Das S, Forrest K, et al. General anaesthesia in elderly patients with cardiovascular disorders: choice of anaesthetic agent. Drugs Aging. 2010; 27(4): 265–82.
Ferrari AU, Radaelli A, et al. Invited review: aging and the cardiovascular system. J Appl Physiol. 2003; 95(6): 259–17.
Fleg JL, Morrell CH, et al. Accelerated longitudinal decline of aerobic capacity in healthy older adults. Circulation. 2005; 112(5): 674–82.
Groban L. Diastolic dysfunction in the older heart. J Cardiothorac Vasc Anesth. 2005; 19(2): 228–36.
Groban L, Butterworth J. Perioperative management of chronic heart failure. Anesth Analg. 2006; 103(3): 557–75.
Hutcheon SD, Gillespie ND, et al. B-type natriuretic peptide in the diagnosis of cardiac disease in elderly day hospital patients. Age Ageing. 2002; 31(4): 295–301.
Janczewski AM, Spurgeon HA, et al. Action potential prolongation in cardiac myocytes of old rats is an adaptation to sustain youthful intracellular Ca2+ regulation. J Mol Cell Cardiol. 2002; 34(6): 641–8.
Jani B, Rajkumar C. Ageing and vascular ageing. Postgrad Med J. 2006; 82(968): 357–62.
Kass DA. Age-related changes in venticular-arterial coupling: pathophysiologic implications. Heart Fail Rev. 2002; 7(1): 51–62.
Kregel KC, Zhang HJ. An integrated view of oxidative stress in aging: basic mechanisms, functional effects, and pathological considerations. Am J Physiol Regul Integr Comp Physiol. 2007; 292(1): R18–36.
Lakatta EG. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part III: cellular and molecular clues to heart and arterial aging. Circulation. 2003; 107(3): 490–7.
Lakatta EG, Levy D. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a “set up” for vascular disease. Circulation. 2003; 107(1): 139–46.
Lakatta EG, Levy D. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part II: the aging heart in health: links to heart disease. Circulation. 2003; 107(2): 346–54.
Lakatta EG, Sollott SJ. Perspectives on mammalian cardiovascular aging: humans to molecules. Comp Biochem Physiol A Mol Integr Physiol. 2002; 132(4): 699–721.
Laurent S, Cockcroft J, et al. Expert consensus document on arterial stiffness: methodological issues and clinical applications. Eur Heart J. 2006; 27(21): 2588–605.
Leung JM, Dzankic S. Relative importance of preoperative health status versus intraoperative factors in predicting postoperative adverse outcomes in geriatric surgical patients. J Am Geriatr Soc. 2001; 49(8): 1080–5.
Liu LL, Dzankic S, et al. Preoperative electrocardiogram abnormalities do not predict postoperative cardiac complications in geriatric surgical patients. J Am Geriatr Soc. 2002; 50(7): 1186–91.
Machado AN, Sitta Mdo C, et al. Prognostic factors for mortality among patients above the 6th decade undergoing non-cardiac surgery: cares–clinical assessment and research in elderly surgical patients. Clinics (Sao Paulo). 2008; 63(2): 151–6.
Najjar SS, Scuteri A, et al. Arterial aging: is it an immutable cardiovascular risk factor? Hypertension. 2005; 46(3): 454–62.
Newsome LT, Kutcher MA, et al. Coronary artery stents: Part I. Evolution of percutaneous coronary intervention. Anesth Analg. 2008; 107(2): 552–69.
Newsome LT, Weller RS, et al. Coronary artery stents: II. Perioperative considerations and management. Anesth Analg. 2008; 107(2): 570–90.
Pimentel AE, Gentile CL, et al. Greater rate of decline in maximal aerobic capacity with age in endurance-trained than in sedentary men. J Appl Physiol. 2003; 94(6): 2406–13.
Poldermans D, Bax JJ, et al. Guidelines for pre-operative cardiac risk assessment and perioperative cardiac management in non-cardiac surgery: the Task Force for Preoperative Cardiac Risk Assessment and Perioperative Cardiac Management in Non-cardiac Surgery of the European Society of Cardiology (ESC) and endorsed by the European Society of Anaesthesiology (ESA). Eur Heart J. 2009; 30(22): 2769–812.
Priebe HJ. The aged cardiovascular risk patient. Br J Anaesth. 2000; 85(5): 763–78.
Pugh KG, Wei JY. Clinical implications of physiological changes in the aging heart. Drugs Aging. 2001; 18(4): 263–76.
Rooke GA. Cardiovascular aging and anesthetic implications. J Cardiothorac Vasc Anesth. 2003; 17(4): 512–23.
Sear JW, Higham H. Issues in the perioperative management of the elderly patient with cardiovascular disease. Drugs Aging. 2002; 19(6): 429–51.
Stathokostas L, Jacob-Johnson S, et al. Longitudinal changes in aerobic power in older men and women. J Appl Physiol. 2004; 97(2): 781–9.
Tay EL, Chan M, et al. Impact of combination evidence-based medical therapy on mortality following myocardial infarction in elderly patients. Am J Geriatr Cardiol. 2008; 17(1): 21–6.
Vaes B, de Ruijter W, et al. The accuracy of plasma natriuretic peptide levels for diagnosis of cardiac dysfunction and chronic heart failure in community-dwelling elderly: a systematic review. Age Ageing. 2009; 38(6): 655–62.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2013 Springer Science+Business Media New York
About this chapter
Cite this chapter
Mitchell, J.D. (2013). Cardiovascular Aging and Anesthesia. In: Barnett, S. (eds) Manual of Geriatric Anesthesia. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-3888-5_14
Download citation
DOI: https://doi.org/10.1007/978-1-4614-3888-5_14
Published:
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4614-3887-8
Online ISBN: 978-1-4614-3888-5
eBook Packages: MedicineMedicine (R0)