Skip to main content

Search

24 result(s) for 'author#Leo MA Heunks' within BMC

Page 1 of 2

Sort by: Relevance | Date

  2. During our medical training, we learned that oxygen administration in patients with chronic obstructive pulmonary disease (COPD) induces hypercapnia through the 'hypoxic drive' mechanism and can be dangerous. ...

    Authors: Wilson F Abdo and Leo MA Heunks
    Citation: Critical Care 2012 16:323
    Content type: Viewpoint Published on:

  3. Expiratory muscle weakness leads to difficult ventilator weaning. Maintaining their activity with functional electrical stimulation (FES) may improve outcome. We studied feasibility of breath-synchronized expi...

    Authors: Annemijn H. Jonkman, Tim Frenzel, Euan J. McCaughey, Angus J. McLachlan, Claire L. Boswell-Ruys, David W. Collins, Simon C. Gandevia, Armand R. J. Girbes, Oscar Hoiting, Matthijs Kox, Eline Oppersma, Marco Peters, Peter Pickkers, Lisanne H. Roesthuis, Jeroen Schouten, Zhong-Hua Shi…
    Citation: Critical Care 2020 24:628
    Content type: Research Published on:

  6. Diaphragm weakness induced by prolonged mechanical ventilation may contribute to difficult weaning from the ventilator. Hypercapnia is an accepted side effect of low tidal volume mechanical ventilation, but th...

    Authors: Willem-Jan M Schellekens, Hieronymus WH van Hees, Matthijs Kox, Marianne Linkels, Gilberto L Andrade Acuña, PN Richard Dekhuijzen, Gert Jan Scheffer, Johannes G van der Hoeven and Leo MA Heunks
    Citation: Critical Care 2014 18:R28
    Content type: Research Published on:

  7. Delivering synchronous assist during non-invasive ventilation (NIV) is challenging with flow- or pressure-controlled ventilators, especially in patients with chronic obstructive pulmonary disease (COPD). Neura...

    Authors: Jonne Doorduin, Christer A Sinderby, Jennifer Beck, Johannes G van der Hoeven and Leo MA Heunks
    Citation: Critical Care 2014 18:550
    Content type: Research Published on:

  8. To better understand the epidemiology and patterns of tracheostomy practice for patients with acute respiratory distress syndrome (ARDS), we investigated the current usage of tracheostomy in patients with ARDS...

    Authors: Toshikazu Abe, Fabiana Madotto, Tài Pham, Isao Nagata, Masatoshi Uchida, Nanako Tamiya, Kiyoyasu Kurahashi, Giacomo Bellani and John G. Laffey
    Citation: Critical Care 2018 22:195
    Content type: Research Published on:

  9. The aim of this study was to describe data on epidemiology, ventilatory management, and outcome of acute respiratory distress syndrome (ARDS) in immunocompromised patients.

    Authors: Andrea Cortegiani, Fabiana Madotto, Cesare Gregoretti, Giacomo Bellani, John G. Laffey, Tai Pham, Frank Van Haren, Antonino Giarratano, Massimo Antonelli, Antonio Pesenti and Giacomo Grasselli
    Citation: Critical Care 2018 22:157
    Content type: Research Published on:

  10. We previously reported that impaired type I IFN activity, due to inborn errors of TLR3- and TLR7-dependent type I interferon (IFN) immunity or to autoantibodies against type I IFN, account for 15–20% of cases ...

    Authors: Daniela Matuozzo, Estelle Talouarn, Astrid Marchal, Peng Zhang, Jeremy Manry, Yoann Seeleuthner, Yu Zhang, Alexandre Bolze, Matthieu Chaldebas, Baptiste Milisavljevic, Adrian Gervais, Paul Bastard, Takaki Asano, Lucy Bizien, Federica Barzaghi, Hassan Abolhassani…
    Citation: Genome Medicine 2023 15:22
    Content type: Research Published on:

    The Correction to this article has been published in Genome Medicine 2024 16:6

  11. Diabetes mellitus is a common co-existing disease in the critically ill. Diabetes mellitus may reduce the risk of acute respiratory distress syndrome (ARDS), but data from previous studies are conflicting. The...

    Authors: Andrew J. Boyle, Fabiana Madotto, John G. Laffey, Giacomo Bellani, Tài Pham, Antonio Pesenti, B. Taylor Thompson, Cecilia M. O’Kane, Adam M. Deane and Daniel F. McAuley
    Citation: Critical Care 2018 22:268
    Content type: Research Published on:

  12. Diaphragm dysfunction develops frequently in ventilated intensive care unit (ICU) patients. Both disuse atrophy (ventilator over-assist) and high respiratory muscle effort (ventilator under-assist) seem to be ...

    Authors: Diana Jansen, Annemijn H. Jonkman, Lisanne Roesthuis, Suvarna Gadgil, Johannes G. van der Hoeven, Gert-Jan J. Scheffer, Armand Girbes, Jonne Doorduin, Christer S. Sinderby and Leo M. A. Heunks
    Citation: Critical Care 2018 22:238
    Content type: Research Published on:

  13. In an effort to reduce the complications related to invasive ventilation, the use of noninvasive ventilation (NIV) has increased over the last years in patients with acute respiratory failure. However, failure...

    Authors: Eline Oppersma, Jonne Doorduin, Erik HFM van der Heijden, Johannes G van der Hoeven and Leo MA Heunks
    Citation: Critical Care 2013 17:245
    Content type: Review Published on:

  14. For every day a person is dependent on mechanical ventilation, respiratory and cardiac complications increase, quality of life decreases and costs increase by > $USD 1500. Interventions that improve respirator...

    Authors: Euan J. McCaughey, Annemijn H. Jonkman, Claire L. Boswell-Ruys, Rachel A. McBain, Elizabeth A. Bye, Anna L. Hudson, David W. Collins, Leo M. A. Heunks, Angus J. McLachlan, Simon C. Gandevia and Jane E. Butler
    Citation: Critical Care 2019 23:261
    Content type: Research Published on:

  15. Concerns exist regarding the prevalence and impact of unnecessary oxygen use in patients with acute respiratory distress syndrome (ARDS). We examined this issue in patients with ARDS enrolled in the Large observa...

    Authors: Fabiana Madotto, Emanuele Rezoagli, Tài Pham, Marcello Schmidt, Bairbre McNicholas, Alessandro Protti, Rakshit Panwar, Giacomo Bellani, Eddy Fan, Frank van Haren, Laurent Brochard and John G. Laffey
    Citation: Critical Care 2020 24:125
    Content type: Research Published on:

  16. Physiological dead space (VD/VT) represents the fraction of ventilation not participating in gas exchange. In patients with acute respiratory distress syndrome (ARDS), VD/VT has prognostic value and can be used t...

    Authors: Jonne Doorduin, Joeke L. Nollet, Manon P. A. J. Vugts, Lisanne H. Roesthuis, Ferdi Akankan, Johannes G. van der Hoeven, Hieronymus W. H. van Hees and Leo M. A. Heunks
    Citation: Critical Care 2016 20:121
    Content type: Research Published on:

  17. Flow starvation is a type of patient-ventilator asynchrony that occurs when gas delivery does not fully meet the patients’ ventilatory demand due to an insufficient airflow and/or a high inspiratory effort, an...

    Authors: Candelaria de Haro, Verónica Santos-Pulpón, Irene Telías, Alba Xifra-Porxas, Carles Subirà, Montserrat Batlle, Rafael Fernández, Gastón Murias, Guillermo M. Albaiceta, Sol Fernández-Gonzalo, Marta Godoy-González, Gemma Gomà, Sara Nogales, Oriol Roca, Tai Pham, Josefina López-Aguilar…
    Citation: Critical Care 2024 28:75
    Content type: Research Published on:

  18. ICU-acquired muscle weakness commonly occurs in patients with septic shock and is associated with poor outcome. Although atrophy is known to be involved, it is unclear whether ligands in plasma from these pati...

    Authors: Hieronymus WH van Hees, Willem-Jan M Schellekens, Marianne Linkels, Floris Leenders, Jan Zoll, Rogier Donders, PN Richard Dekhuijzen, Johannes G van der Hoeven and Leo MA Heunks
    Citation: Critical Care 2011 15:R233
    Content type: Research Published on:

  19. Patients with acute respiratory failure caused by cardiogenic pulmonary edema (CPE) may require mechanical ventilation that can cause further lung damage. Our aim was to determine the impact of ventilatory set...

    Authors: Laura Amado-Rodríguez, Raquel Rodríguez-Garcia, Giacomo Bellani, Tài Pham, Eddy Fan, Fabiana Madotto, John G. Laffey and Guillermo M. Albaiceta
    Citation: Journal of Intensive Care 2022 10:55
    Content type: Research Published on:

  20. Controlled mechanical ventilation and endotoxemia are associated with diaphragm muscle atrophy and dysfunction. Oxidative stress and activation of inflammatory pathways are involved in the pathogenesis of diap...

    Authors: Willem-Jan M Schellekens, Hieronymus WH van Hees, Marianne Linkels, PN Richard Dekhuijzen, Gert Jan Scheffer, Johannes G van der Hoeven and Leo MA Heunks
    Citation: Critical Care 2015 19:69
    Content type: Research Published on: