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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 1
1953 2
1967 3
1970 2
1972 3
1973 1
1974 4
1975 79
1976 68
1977 78
1978 89
1979 76
1980 108
1981 120
1982 125
1983 148
1984 138
1985 138
1986 146
1987 168
1988 176
1989 196
1990 223
1991 202
1992 241
1993 231
1994 239
1995 290
1996 264
1997 293
1998 335
1999 326
2000 388
2001 384
2002 410
2003 448
2004 549
2005 575
2006 543
2007 622
2008 706
2009 658
2010 753
2011 865
2012 905
2013 965
2014 1064
2015 1259
2016 913
2017 758
2018 1052
2019 1134
2020 1188
2021 1262
2022 1145
2023 914
2024 154

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21,804 results

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Page 1
Diagnosis and management of Stevens-Johnson syndrome/toxic epidermal necrolysis.
Noe MH, Micheletti RG. Noe MH, et al. Clin Dermatol. 2020 Nov-Dec;38(6):607-612. doi: 10.1016/j.clindermatol.2020.06.016. Epub 2020 Jun 30. Clin Dermatol. 2020. PMID: 33341195 Review.
Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a rare, immunologically mediated cutaneous adverse reaction characterized by mucous membrane and epidermal detachment, with a mortality ranging from 15% to 25%. ...Medications are the most common cause, parti …
Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a rare, immunologically mediated cutaneous adverse reaction characte …
T-cell receptor and carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: understanding a hypersensitivity reaction.
Ko TM, Chen YT. Ko TM, et al. Expert Rev Clin Immunol. 2012 Jul;8(5):467-77. doi: 10.1586/eci.12.31. Expert Rev Clin Immunol. 2012. PMID: 22882221 Review.
Ample evidence exists to support the view that drug hypersensitivity is mediated by adaptive immunity, which involves MHC-restricted drug presentation, activation and clonal expansion of T cells. The specific MHC molecules implicated in hypersensitivity have been identifie …
Ample evidence exists to support the view that drug hypersensitivity is mediated by adaptive immunity, which involves MHC-restricted drug pr …
ALDEN, an algorithm for assessment of drug causality in Stevens-Johnson Syndrome and toxic epidermal necrolysis: comparison with case-control analysis.
Sassolas B, Haddad C, Mockenhaupt M, Dunant A, Liss Y, Bork K, Haustein UF, Vieluf D, Roujeau JC, Le Louet H. Sassolas B, et al. Clin Pharmacol Ther. 2010 Jul;88(1):60-8. doi: 10.1038/clpt.2009.252. Epub 2010 Apr 7. Clin Pharmacol Ther. 2010. PMID: 20375998
Epidermal necrolysis (EN)--either Stevens-Johnson syndrome (SJS) or toxic EN (TEN)--is a severe drug reaction. ...
Epidermal necrolysis (EN)--either Stevens-Johnson syndrome (SJS) or toxic EN (TEN)--is a severe drug reaction. ...
Carbamazepine Induces Focused T Cell Responses in Resolved Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Cases But Does Not Perturb the Immunopeptidome for T Cell Recognition.
Mifsud NA, Illing PT, Lai JW, Fettke H, Hensen L, Huang Z, Rossjohn J, Vivian JP, Kwan P, Purcell AW. Mifsud NA, et al. Front Immunol. 2021 Apr 12;12:653710. doi: 10.3389/fimmu.2021.653710. eCollection 2021. Front Immunol. 2021. PMID: 33912179 Free PMC article.
What is less understood are the long-lived immunological effects of the memory T cell pool following T cell-mediated drug hypersensitivity reactions. In this study, we examine the ASM carbamazepine (CBZ) and the CBZ-reactive memory T cell pool in patients who …
What is less understood are the long-lived immunological effects of the memory T cell pool following T cell-mediated drug hype …
Current Pharmacogenetic Perspective on Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.
Cheng L. Cheng L. Front Pharmacol. 2021 Apr 26;12:588063. doi: 10.3389/fphar.2021.588063. eCollection 2021. Front Pharmacol. 2021. PMID: 33981213 Free PMC article. Review.
Though T-cell-mediated HLA-interacted immune response has been extensively studied, our understanding of the mechanism is far from satisfactory. ...Epigenetics, metabolites, and mobilization of regulatory T cells and tolerogenic myeloid precursors are emerged direct …
Though T-cell-mediated HLA-interacted immune response has been extensively studied, our understanding of the mechanism is far from sa …
New insights into the diagnosis and management of Stevens-Johnson syndrome and toxic epidermal necrolysis.
Saito Y, Abe R. Saito Y, et al. Curr Opin Allergy Clin Immunol. 2023 Aug 1;23(4):271-278. doi: 10.1097/ACI.0000000000000914. Epub 2023 Jun 6. Curr Opin Allergy Clin Immunol. 2023. PMID: 37284785 Review.
PURPOSE OF REVIEW: Recent studies have been clarifying the pathogenesis and early diagnostic markers of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). ...As the involvement of innate immunity, such as monocytes and neutrophils, in addition to T …
PURPOSE OF REVIEW: Recent studies have been clarifying the pathogenesis and early diagnostic markers of Stevens-Johnson syndrome (SJS …
Stevens-Johnson syndrome and toxic epidermal necrolysis: risk factors, causality assessment and potential prevention strategies.
Lin CC, Chen CB, Wang CW, Hung SI, Chung WH. Lin CC, et al. Expert Rev Clin Immunol. 2020 Apr;16(4):373-387. doi: 10.1080/1744666X.2020.1740591. Epub 2020 Apr 2. Expert Rev Clin Immunol. 2020. PMID: 32154748 Review.
Introduction: The clinical manifestations of cutaneous adverse drug reactions are variable with different severity. Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening severe cutaneous adverse reactions (SCARs) majorly caused by drugs a …
Introduction: The clinical manifestations of cutaneous adverse drug reactions are variable with different severity. Stevens-Johnson s …
T cell-mediated hypersensitivity reactions to drugs.
Pavlos R, Mallal S, Ostrov D, Buus S, Metushi I, Peters B, Phillips E. Pavlos R, et al. Annu Rev Med. 2015;66:439-54. doi: 10.1146/annurev-med-050913-022745. Epub 2014 Oct 27. Annu Rev Med. 2015. PMID: 25386935 Free PMC article. Review.
The immunological mechanisms driving delayed hypersensitivity reactions (HSRs) to drugs mediated by drug-reactive T lymphocytes are exemplified by several key examples and their human leukocyte antigen (HLA) associations: abacavir and HLA-B*57:01, carbamazepine and HLA-B*1 …
The immunological mechanisms driving delayed hypersensitivity reactions (HSRs) to drugs mediated by drug-reactive T lymphocytes are e …
Optic Nerve Aplasia.
Saffren BD, Yassin SH, Geddie BE, de Faber JTHN, Blieden LS, Bhate M, Gamio S, Rutar T, Levin AV. Saffren BD, et al. J Neuroophthalmol. 2022 Mar 1;42(1):e140-e146. doi: 10.1097/WNO.0000000000001246. Epub 2021 Apr 14. J Neuroophthalmol. 2022. PMID: 33870948
T. G. STEVENS.
[No authors listed] [No authors listed] Br Med J. 1953 Nov 21;2(4846):1163. Br Med J. 1953. PMID: 13106368 Free PMC article. No abstract available.
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