Eurasian back-migration into Northeast Africa was a complex and multifaceted process

PLoS One. 2023 Nov 8;18(11):e0290423. doi: 10.1371/journal.pone.0290423. eCollection 2023.

Abstract

Recent studies have identified Northeast Africa as an important area for human movements during the Holocene. Eurasian populations have moved back into Northeastern Africa and contributed to the genetic composition of its people. By gathering the largest reference dataset to date of Northeast, North, and East African as well as Middle Eastern populations, we give new depth to our knowledge of Northeast African demographic history. By employing local ancestry methods, we isolated the Non-African parts of modern-day Northeast African genomes and identified the best putative source populations. Egyptians and Sudanese Copts bore most similarities to Levantine populations whilst other populations in the region generally had predominantly genetic contributions from the Arabian peninsula rather than Levantine populations for their Non-African genetic component. We also date admixture events and investigated which factors influenced the date of admixture and find that major linguistic families were associated with the date of Eurasian admixture. Taken as a whole we detect complex patterns of admixture and diverse origins of Eurasian admixture in Northeast African populations of today.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Africa
  • Arabia
  • Black People* / genetics
  • Egypt
  • Genetics, Population*
  • Human Migration*
  • Humans
  • White People* / genetics

Grants and funding

The project was funded by the European Research Council (ERC StG AfricanNeo, grant no. 759933) and the Knut and Alice Wallenberg Fellowship grant. Computations were enabled by resources provided by the Swedish National Infrastructure for Computing (SNIC) at UPPMAX, partially funded by the Swedish Research Council (through grant agreement no. 2018-05973). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. The salaries of C.S. and R.H. was funded by the European Research Council (ERC StG AfricanNeo, grant no. 759933) and the Knut and Alice Wallenberg Fellowship grant.