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Fragile Mitochondrial DNA: The Missing Link in the Apoptotic Neuronal Cell Death in Parkinson's Disease☆
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Abbreviations: PD, Parkinson's diseaseAD, Alzheimer's disease; ALS, amyotrophic lateral screlosis; CM, cardiomyopathy; HCM, hypertrophic cardiomyopathy; DCM, dilated cardiomyopathy; ND, NADH dehydrogenase; MPP+, 1-methyl-4-phenylpyridinium ion; PCR, polymerase chain reaction; mt, mitochondrial; n, nuclear; Δ, deleted; ω, wild-type; kbp, kilo base-pair; np, nucleotide position; Or, replication origin; •OH, hydroxyl radical; 8-OH-dG, 8-hydroxy-deoxyguanosine;
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