mRNA Therapies: New Hope in the Fight against Melanoma
Published as part of the Biochemistry series “Biochemistry to Bedside”
- Melissa van Dülmen
Melissa van DülmenDepartment of Chemistry and Pharmacy, Institute for Biochemistry, University of Münster, Wilhelm-Klemm-Straße 2, 48149 Münster, GermanyMore by Melissa van Dülmen
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- Andrea Rentmeister*
Andrea Rentmeister*Email: [email protected]Department of Chemistry and Pharmacy, Institute for Biochemistry, University of Münster, Wilhelm-Klemm-Straße 2, 48149 Münster, GermanyCells in Motion Interfaculty Center, Waldeyerstraße 15, 48149 Münster, GermanyMore by Andrea Rentmeister
Abstract
Melanoma is a life-threatening disease caused by mutations in pigment-producing cells. Numerous treatments for melanoma have been approved in the past several decades; however, they often cause severe side effects and in most cases do not result in a complete cure. mRNA (messenger RNA) as a therapeutic agent provides a new avenue for melanoma treatment and several advantages over conventional treatments. The first mRNA drugs for melanoma treatment are currently in clinical trials, and approval of mRNA drugs by the Food and Drug Administration seems to be within reach. This new class of drugs can be readily adapted to other diseases, raising the hope of providing a new therapeutic option for various diseases.
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