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Human Hematopoiesis in SCID Mice

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Human Hematopoiesis in SCID Mice

Part of the book series: Medical Intelligence Unit ((MIU.LANDES))

Abstract

The hematopoietic system is organized as a hierarchy where the majority of the cells are mature, and therefore, need to be continuously replenished from a small pool of immature progenitors. Ultimately, the entire hematopoietic system is derived from stem cells that have extensive proliferative and differentiation capacity and give rise to all myeloid and lymphoid lineages. Insight into the biology of these stem cells is, therefore, fundamental to our understanding of the regulation of normal and abnormal hematopoiesis.

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Authors
  1. Josef Vormoor
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  2. Tsvee Lapidot
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  3. André Larochelle
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  4. John E. Dick
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© 1995 Springer-Verlag Berlin Heidelberg

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Vormoor, J., Lapidot, T., Larochelle, A., Dick, J.E. (1995). Human Hematopoiesis in SCID Mice. In: Human Hematopoiesis in SCID Mice. Medical Intelligence Unit. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-22008-5_10

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  • DOI: https://doi.org/10.1007/978-3-662-22008-5_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-22010-8

  • Online ISBN: 978-3-662-22008-5

  • eBook Packages: Springer Book Archive

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