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Cardiovascular Physiology and Fluid Shifts in Space

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Spaceflight and the Central Nervous System

Abstract

Central nervous system vasculature (venous and arterial blood) and the cerebrospinal fluid dynamics are predominant systems which are hugely affected during spaceflight by many factors such as radiation and microgravity. Therefore, the human body should adapt by various mechanisms in such an environment. In this chapter, we will highlight the normal physiology and dynamics of cardiovascular system on Earth and how the body adapt in the long- and short-term space flights, in addition to the importance of these adaptations to the central nervous system and discuss common syndromes such as space adaptation syndrome and visual impairment intracranial pressure (VIIP) syndrome that may affect the mission quality, and effective countermeasures to mitigate these effects such as artificial gravity and lower body negative pressure (LBNP).

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Authors and Affiliations

  1. Department of Medicine, Ain Shams University, Cairo, Egypt

    Aya Hesham Sayed

  2. Department of Orthopaedic Surgery, University of California, San Diego, Altman Clinical and Translational Research Institute, La Jolla, CA, USA

    Alan R. Hargens

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Correspondence to Aya Hesham Sayed .

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Editors and Affiliations

  1. Neurological Surgeon, Mercy Clinic Neurosurgery, Saint Louis, MO, USA

    Alex P. Michael

  2. Director of Teleoncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA

    Christian Otto

  3. NASA Neuroscience, Johnson Space Center, Houston, TX, USA

    Millard F. Reschke

  4. Department of Orthopaedic Surgery, University of California, San Diego, La Jolla, CA, USA

    Alan R. Hargens

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Sayed, A.H., Hargens, A.R. (2022). Cardiovascular Physiology and Fluid Shifts in Space. In: Michael, A.P., Otto, C., Reschke, M.F., Hargens, A.R. (eds) Spaceflight and the Central Nervous System. Springer, Cham. https://doi.org/10.1007/978-3-031-18440-6_2

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