Article Text
Acute paediatrics
Role of itraconazole in haematology/oncology
Abstract
The antifungal agents most frequently used in prophylaxis and treatment are amphotericin B (and its new lipid forms) and azoles such as fluconazole, itraconazole, and more recently voriconazole. This review assesses the role of itraconazole in paediatric haematology/oncology practice. Its broader spectrum of activity and availability in oral and intravenous forms allow a flexible approach in the management of fungal infections.
- itraconazole
- invasive fungal infections
- prophylaxis
- GVHD, graft versus host disease
- IFI, invasive fungal infections