Daily supplementation with 15 μg vitamin D2 compared with vitamin D3 to increase wintertime 25-hydroxyvitamin D status in healthy South Asian and white European women: a 12-wk randomized, placebo-controlled food-fortification trial
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Key Words
vitamin D
vitamin D2
vitamin D3
25-hydroxyvitamin D
randomized controlled trial
food fortification
healthy women
South Asian
white European
Abbreviations
D2B
placebo juice with biscuit supplemented with 15 μg vitamin D2
D2J
juice supplemented with 15 μg vitamin D2 with placebo biscuit
D3B
placebo juice with biscuit supplemented with 15 μg vitamin D3
D3J
juice supplemented with 15 μg vitamin D3 with placebo biscuit
EPD
estimated percentage difference
HPLC-MS/MS
HPLC–tandem mass spectrometry
IOM
Institute of Medicine
PTH
parathyroid hormone
RDA
Recommended Daily Allowance
SED
standard erythemal dose
25(OH)D
25-hydroxyvitamin D
25(OH)D2
25-hydroxyvitamin D2
25(OH)D3
25-hydroxyvitamin D3.
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Supported by the United Kingdom–based Biotechnology and Biological Sciences Research Council (BBSRC) as part of a BBSRC Diet and Health Research Industry Club grant (BB/I006192/1). The funder had no role in the design, implementation, analysis, or interpretation of the research. LT was the recipient of a Young Investigator Award at the 2014 National Osteoporosis Society Conference (Birmingham, United Kingdom) for the vitamin D2 compared with vitamin D3 findings. LRW received the Postgraduate Award at the 2016 Nutrition Society’s 75th Anniversary Conference (Dublin, Republic of Ireland) for vitamin D food fortification and the D2-D3 Study findings.
Copyright © 2017 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.