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Pharmacological studies on a plant lectin, Aloctin A. I. Growth inhibition of mouse methylcholanthrene-induced fibrosarcoma (Meth A) in ascites form by Aloctin A

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Summary

A glycoprotein isolated fromAloe arborescens Mill markedly inhibited the growth of a syngeneic transplantable fibrosarcoma of mice, Meth A, in ascites form. There is evidence that the inhibition mechanism is host-mediated and not a direct toxic effect on the tumor cell.

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Author notes

  1. T. Ishiguro

    Present address: The Koriyama Institute of Medical Immunology, 963, Koriyama, Japan

Authors and Affiliations

  1. Laboratory of Ultrastructure Research, Aichi Cancer Center Research Institute, 464, Nagoya, Japan

    K. Imanishi, T. Ishiguro, H. Saito & I. Suzuki

Authors
  1. K. Imanishi
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  2. T. Ishiguro
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  3. H. Saito
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  4. I. Suzuki
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Additional information

Acknowledgment. We thank Miss M. Hayama for her technical help.

To whom all correspondence should be addressed.

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Imanishi, K., Ishiguro, T., Saito, H. et al. Pharmacological studies on a plant lectin, Aloctin A. I. Growth inhibition of mouse methylcholanthrene-induced fibrosarcoma (Meth A) in ascites form by Aloctin A. Experientia 37, 1186–1187 (1981). https://doi.org/10.1007/BF01989910

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  • DOI: https://doi.org/10.1007/BF01989910

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