Treatment of Ocular Surface Squamous Neoplasia With Topical Aloe vera Drops : Cornea

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Case Report

Treatment of Ocular Surface Squamous Neoplasia With Topical Aloe vera Drops

Damani, Mausam R. MD; Shah, Ankoor R. MD; Karp, Carol L. MD; Orlin, Stephen E. MD

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Cornea 34(1):p 87-89, January 2015. | DOI: 10.1097/ICO.0000000000000296

Abstract

Purpose: 

To report a case of ocular surface squamous neoplasia (OSSN) that resolved with topical Aloe vera eye drop treatment.

Methods: 

A 64-year-old Hispanic woman with a lesion typical for OSSN in her left eye was followed up with multiple clinical examinations and ocular surface photographs to document changes over time with A. vera-based topical treatment.

Results: 

The patient refused biopsy of her lesion and traditional treatments and, instead, initiated using A. vera eye drops 3 times daily. At follow-up visits, the lesion was noted to regress until it finally resolved 3 months after commencing treatment. No additional topical medications were used, and she has remained tumor free for 6 years.

Conclusions: 

Ongoing research is warranted because A. vera may represent a new therapeutic class of medications for OSSN treatment.

Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.

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