N3C Privacy-Preserving Record Linkage and Linked Data Governance

Table of Contents

• Background 2
• N3C Privacy Preserving Record Linkage Principles 2
• PPRL Participation Options 4
• Deduplication 4
• Linking Multiple Datasets 5
• Cohort Discovery for Research Studies 7
• Technical and Data Governance Architecture for N3C PPRL Linked Data Infrastructure 9
• Appendix A Glossary 12
• Appendix B Linkage Honest Broker Agreement 13
• Appendix C Regulatory Considerations for Privacy-Preserving Record Linkage 27