Abstract
Vitamin C was first suggested to have cancer-fighting properties in the 1930s and has been the subject of controversy ever since. Despite repeated reports of selective cancer cell toxicity induced by high-dose vitamin C treatment in vitro and in mouse models, the mechanism of action has remained elusive.
MeSH terms
- Animals
- Ascorbic Acid / therapeutic use*
- Colorectal Neoplasms / drug therapy*
- Colorectal Neoplasms / genetics*
- Female
- Humans
- Proto-Oncogene Proteins / genetics*
- Proto-Oncogene Proteins B-raf / genetics*
- ras Proteins / genetics*
Substances
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins B-raf
- ras Proteins
- Ascorbic Acid