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Additive Effects of PDGF Receptor β Signaling Pathways in Vascular Smooth Muscle Cell Development

Figure 3

Tissue Localization of V/P Cell Markers and PDGFRα Expression

Tissue preparations from P21 PDGFRαGFP/+;PDGFRβF5/F5 mutant mouse. Immunofluorescence was used to detect αSMA (A and B), desmin (C), β-galactosidase (D), and GFP expression for PDGFRα (A–D). (A) Kidney (200 μm vibratome section). The arrow indicates glomerulus. The asterisk indicates an arteriole. (B–D) Retina (whole-mount preparation). Arrowheads point to β-galactosidase-positive nuclei.

Figure 3

doi: https://doi.org/10.1371/journal.pbio.0000052.g003