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Additive Antinociceptive Effects of a Combination of Vitamin C and Vitamin E after Peripheral Nerve Injury

Figure 8

Long-term treatment with low dose Vit C and Vit E does not inhibit CFA-induced inflammatory pain behavior.

Mice were injected with 20 µl CFA into a hindpaw and drugs were i.p. administered at the indicated doses once daily for 12 days starting immediately after CFA injection. Paw withdrawal latency times upon mechanical stimulation are shown. Statistical analyses revealed no significant differences between groups. n = 8 per group.

Figure 8

doi: https://doi.org/10.1371/journal.pone.0029240.g008