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21 result(s) for 'author#Patrick N Harter' within BMC
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Citation: Fluids and Barriers of the CNS 2021 18(Suppl 1):58
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Supported Decision-Making for Persons with Mental Illness: A Review
Persons with mental illness (PWMI) are often not afforded the same opportunity to make decisions on a par with others in society. Article 12 of the International Convention on the Rights of Persons with Disabi...
Citation: Public Health Reviews 2012 34:15 -
Assessment of the structure of the Hospital Anxiety and Depression Scale in musculoskeletal patients
Research suggests there is a high prevalence of anxiety and depression amongst patients with chronic musculoskeletal pain, which can influence the effectiveness of rehabilitation programs. It is therefore impo...
Citation: Health and Quality of Life Outcomes 2005 3:82 -
Proceedings from the 12th Annual Conference on the Science of Dissemination and Implementation
Citation: Implementation Science 2020 15(Suppl 1):25 -
Reviewer acknowledgement 2015
The editors of BMC Public Health would like to thank all our reviewers who have contributed to the journal in Volume 15 (2015).
Citation: BMC Public Health 2016 16:189 -
Proceedings of the 16th annual conference of INEBRIA
Citation: Addiction Science & Clinical Practice 2019 14(Suppl 1):27 -
Evaluation of automatic discrimination between benign and malignant prostate tissue in the era of high precision digital pathology
Prostate cancer is a major health concern in aging men. Paralleling an aging society, prostate cancer prevalence increases emphasizing the need for efficient diagnostic algorithms.
Citation: BMC Bioinformatics 2023 24:1 -
Cholinergic innervation and ganglion cell distribution in Hirschsprung’s disease
The diagnostic gold standard of Hirschsprung’s disease (HD) is based on the histopathological assessment of colorectal biopsies. Although data on cholinergic innervation and ganglion cell (GC) distribution exi...
Citation: BMC Pediatrics 2020 20:399 -
The impact of referring patients with drug-resistant focal epilepsy to an epilepsy center for presurgical diagnosis
Epilepsy surgery is an established treatment for drug-resistant focal epilepsy (DRFE) that results in seizure freedom in about 60% of patients. Correctly identifying an epileptogenic lesion in magnetic resonan...
Citation: Neurological Research and Practice 2023 5:65 -
Impact of Docetaxel on blood-brain barrier function and formation of breast cancer brain metastases
Breast cancer (BC) is the most frequent malignant tumor in females and the 2nd most common cause of brain metastasis (BM), that are associated with a fatal prognosis. The increasing incidence from 10% up to 40...
Citation: Journal of Experimental & Clinical Cancer Research 2019 38:434 -
Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy
Even in the presence of oxygen, malignant cells often highly depend on glycolysis for energy generation, a phenomenon known as the Warburg effect. One strategy targeting this metabolic phenotype is glucose res...
Citation: BMC Cancer 2011 11:315 -
The FREGAT biobank: a clinico-biological database dedicated to esophageal and gastric cancers
While the incidence of esophageal and gastric cancers is increasing, the prognosis of these cancers remains bleak. Endoscopy and surgery are the standard treatments for localized tumors, but multimodal treatme...
Citation: BMC Cancer 2018 18:139 -
Pleomorphic xanthoastrocytoma is a heterogeneous entity with pTERT mutations prognosticating shorter survival
Pleomorphic xanthoastrocytoma (PXA) in its classic manifestation exhibits distinct morphological features and is assigned to CNS WHO grade 2 or grade 3. Distinction from glioblastoma variants and lower grade g...
Citation: Acta Neuropathologica Communications 2022 10:5 -
Akt and mTORC1 signaling as predictive biomarkers for the EGFR antibody nimotuzumab in glioblastoma
Glioblastoma (GB) is the most frequent primary brain tumor in adults with a dismal prognosis despite aggressive treatment including surgical resection, radiotherapy and chemotherapy with the alkylating agent t...
Citation: Acta Neuropathologica Communications 2018 6:81 -
β-Catenin-Gli1 interaction regulates proliferation and tumor growth in medulloblastoma
The Wnt/beta-catenin and the Hedgehog (Hh) pathway interact in various cell types while eliciting opposing or synergistic cellular effects. Both pathways are known as exclusive drivers of two distinct molecula...
Citation: Molecular Cancer 2015 14:17 -
EpiDiP/NanoDiP: a versatile unsupervised machine learning edge computing platform for epigenomic tumour diagnostics
DNA methylation analysis based on supervised machine learning algorithms with static reference data, allowing diagnostic tumour typing with unprecedented precision, has quickly become a new standard of care. W...
Citation: Acta Neuropathologica Communications 2024 12:51 -
Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation
PINK1 deficiency causes the autosomal recessive PARK6 variant of Parkinson’s disease. PINK1 activates ubiquitin by phosphorylation and cooperates with the downstream ubiquitin ligase PARKIN, to exert quality c...
Citation: Journal of Neuroinflammation 2017 14:154 -
CD74 regulates complexity of tumor cell HLA class II peptidome in brain metastasis and is a positive prognostic marker for patient survival
Despite multidisciplinary local and systemic therapeutic approaches, the prognosis for most patients with brain metastases is still dismal. The role of adaptive and innate anti-tumor response including the Hum...
Citation: Acta Neuropathologica Communications 2018 6:18 -
Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis
Melanoma patients carry a high risk of developing brain metastases, and improvements in survival are still measured in weeks or months. Durable disease control within the brain is impeded by poor drug penetrat...
Citation: Acta Neuropathologica Communications 2019 7:55 -
ORGAVADS: establishment of tumor organoids from head and neck squamous cell carcinoma to assess their response to innovative therapies
Radiotherapy is one of the cornerstones of the treatment of Head and Neck Squamous Cell Carcinomas (HNSCC). However, radioresistance is associated with a high risk of recurrence. To propose strategies (such as co...
Citation: BMC Cancer 2023 23:223