Prevalence, Demographics, and Psychological Associations of Sleep Disruption in Patients With Cancer: University of Rochester Cancer Center–Community Clinical Oncology Program
Abstract
Purpose
Patients and Methods
Results
Conclusion
Introduction
Patients and Methods
Assessments
Demographics.
Insomnia.
Statistical Methods
Data reduction.
Data analyses.
Results
Patient Sample
Characteristic | No Symptoms | Some Insomnia Symptoms | Clinical Insomnia | |||
---|---|---|---|---|---|---|
No. of Patients | % | No. of Patients | % | No. of Patients | % | |
Age, years | ||||||
Mean | 61.3 | 57 | 55.9 | |||
SE | 0.08 | 0.04 | 0.03 | |||
Diagnosis | ||||||
Alimentary tract | 27 | 36 | 30 | 40 | 18 | 24 |
Brain and peripheral | 1 | 33.3 | 1 | 33.3 | 1 | 33.3 |
Breast | 61 | 15.3 | 156 | 39 | 183 | 45.8 |
Genitourinary tract | 6 | 21.4 | 7 | 25 | 15 | 53.6 |
Gynecologic | 11 | 17.2 | 25 | 39.1 | 28 | 43.8 |
Hematologic | 23 | 19.5 | 44 | 37.3 | 51 | 43.2 |
Lung | 24 | 20 | 35 | 29.2 | 61 | 50.8 |
Melanoma | 0 | 0 | 0 | 0 | 1 | 100 |
Neck and head | 3 | 75 | 0 | 0 | 1 | 25 |
Soft tissue sarcoma | 1 | 33.3 | 1 | 33.3 | 1 | 33.3 |
Unknown primary | 3 | 42.9 | 2 | 28.6 | 2 | 28.6 |
Marital status | ||||||
Married | 106 | 18.2 | 220 | 37.7 | 257 | 44.1 |
Divorced | 16 | 18.6 | 25 | 29.1 | 45 | 52.3 |
Separated | 3 | 30 | 1 | 10 | 6 | 60 |
Single | 14 | 23 | 22 | 36.1 | 25 | 41 |
Widowed | 21 | 25.3 | 33 | 39.8 | 29 | 34.9 |
Race | ||||||
American Indian | 4 | 66.7 | 0 | 0 | 2 | 33.3 |
Black | 16 | 28.1 | 17 | 29.8 | 24 | 42.1 |
Hawaiian/Pacific Islander | 4 | 19 | 10 | 47.6 | 7 | 33.3 |
Non-Hispanic | 2 | 14.3 | 3 | 21.4 | 9 | 64.3 |
Unknown | 0 | 0 | 0 | 0 | 3 | 100 |
White | 134 | 18.6 | 271 | 37.5 | 317 | 43.9 |
Ethnicity | ||||||
Nonwhite | 26 | 25.7 | 30 | 29.7 | 45 | 44.6 |
White | 134 | 18.6 | 271 | 37.5 | 317 | 43.9 |
Sex, female | 106 | 17.7 | 229 | 38.3 | 263 | 44.0 |
Previous treatment | ||||||
Surgery | 95 | 17.9 | 204 | 38.3 | 233 | 43.8 |
Chemotherapy | 21 | 17.9 | 56 | 47.9 | 40 | 34.2 |
Radiation | 21 | 24.4 | 28 | 32.6 | 37 | 43.0 |
Other | 147 | 20.2 | 271 | 37.3 | 309 | 42.5 |
Other disease characteristics | ||||||
Adjuvant | 94 | 17.8 | 186 | 35.3 | 247 | 46.9 |
Metastatic | 60 | 22.7 | 100 | 37.9 | 104 | 39.4 |
Neoadjuvant | 3 | 33.3 | 6 | 66.7 | 0 | 0 |
Other | 2 | 15.4 | 5 | 38.5 | 6 | 46.2 |
Recurrent | 1 | 14.3 | 3 | 42.9 | 3 | 42.9 |
Insomnia During Chemotherapy
Insomnia by Diagnosis
Insomnia at Cycles 1 and 2
Insomnia Levels at Cycle 1 | Insomnia Levels at Cycle 2 | ||
---|---|---|---|
Insomnia Syndrome (%) | Insomnia Symptoms (%) | Good Sleepers (%) | |
Insomnia syndrome (n = 317) | 65.3 | 28.4 | 6.3 |
Insomnia symptoms (n = 276) | 25.0 | 53.3 | 21.7 |
Good sleepers (n = 142) | 9.9 | 24.6 | 65.5 |
Sex
Age
Sex, Age, and Race
Insomnia by Fatigue and Depression
Discussion
J Clin Oncol Palesh et al 10.1200/JCO.2009.22.5011
Publisher’s Note
In the References section, reference 32 should have been cited as reference 4a.
In the text, reference 4a should have been cited instead of reference 5 in the following sentences: the last sentence of the second paragraph of the Introduction section, the second sentence of the second paragraph of the Patients and Methods section under Statistical Methods, the second sentence of the Results section under Insomnia During Chemotherapy, and the second sentence of the first paragraph and the second sentence of the second paragraph of the Discussion section. In addition, reference 4a should have been cited instead of reference 32 in the second sentence of the Results section under Insomnia During Chemotherapy, and in the legend for Figure 1.
In the References section and in the text, references 33-37 should have been cited as references 32-36, respectively.
Reference 36 should have been:
Ohayon MM, Roth T: What are the contributing factors for insomnia in the general population? J Psychosom Res 51:745-755, 2001
Reference 37 should have been:
Mao J, Armstrong K, Bowman M: Symptom burden among cancer survivors: Impact of age and comorbidity. JABFM 20:434-44, 2007
In the Discussion section, reference 37 should have been cited in the third sentence of the second paragraph instead of reference 34.
All corrections have been made as of December 10, 2009. The authors apologize to the readers for these mistakes.
Authors' Disclosures of Potential Conflicts of Interest
References
Appendix
Scale | Insomnia Syndrome | Insomnia Symptoms | Good Sleepers | |||
---|---|---|---|---|---|---|
Mean | SD | Mean | SD | Mean | SD | |
FSCL | 59.34 | 19.55 | 46.77 | 15.53 | 43.55 | 17.40 |
POMS-Total | 20.48 | 18.55 | 7.82 | 15.36 | 2.85 | 15.35 |
POMS-V | 3.84 | 3.80 | 5.51 | 4.42 | 6.02 | 4.65 |
POMS-F | 9.38 | 5.43 | 5.85 | 4.71 | 4.65 | 5.38 |
POMS TA | 5.60 | 4.07 | 3.27 | 3.06 | 2.12 | 2.80 |
POMS-DD | 4.21 | 4.15 | 2.32 | 2.94 | 1.35 | 2.32 |
POMS-AH | 3.70 | 3.90 | 1.86 | 2.70 | 1.13 | 2.03 |
POMS-CB | 1.43 | 3.34 | 0.03 | 2.56 | −.37 | 2.86 |
MAF | 5.89 | 2.55 | 4.55 | 2.67 | 3.87 | 2.97 |
CES-D | 18.69 | 10.51 | 11.32 | 8.46 | 7.59 | 7.84 |
Information & Authors
Information
Published In
Copyright
History
Authors
Author Contributions
Disclosures
Funding Information
Metrics & Citations
Metrics
Altmetric
Citations
Article Citation
Download Citation
If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download.
For more information or tips please see 'Downloading to a citation manager' in the Help menu.
Journal of Clinical Oncology 2010 28:2, 292-298
View Options
View options
Get Access
Login options
Check if you have access through your login credentials or your institution to get full access on this article.
Personal login Institutional LoginPurchase Options
Purchase this article to get full access to it.
Subscribe
Subscribe to this Journal
Renew Your Subscription
Become a Member