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December 12, 2005

Low-glycemic-index treatment: A liberalized ketogenic diet for treatment of intractable epilepsy

December 13, 2005 issue
65 (11) 1810-1812

Abstract

The ketogenic diet is often effective for intractable epilepsy, but many patients have trouble complying with the strict regimen. The authors tested an alternative diet regimen, a low-glycemic-index treatment, with more liberal total carbohydrate intake but restricted to foods that produce relatively little increase in blood glucose (glycemic index < 50). Ten of 20 patients treated with this regimen experienced a greater than 90% reduction in seizure frequency.

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Information & Authors

Information

Published In

Neurology®
Volume 65Number 11December 13, 2005
Pages: 1810-1812
PubMed: 16344529

Publication History

Published online: December 12, 2005
Published in print: December 13, 2005

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Authors

Affiliations & Disclosures

Heidi H. Pfeifer, RD, LDN
From the Pediatric Epilepsy Program, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA.
Elizabeth A. Thiele, MD, PhD
From the Pediatric Epilepsy Program, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA.

Notes

Address correspondence and reprint requests to Dr. Elizabeth A. Thiele, Pediatric Epilepsy Service, Massachusetts General Hospital, 175 Cambridge St., Suite 340, Boston, MA 02114; e-mail: [email protected]

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