Clinical Endocrinology

Volume 93, Issue 4 p. 508-511

LETTER TO THE EDITOR

Low serum 25-hydroxyvitamin D (25[OH]D) levels in patients hospitalized with COVID-19 are associated with greater disease severity

Grigorios Panagiotou,

Grigorios Panagiotou

orcid.org/0000-0003-0690-1478

Department of Endocrinology, Diabetes & Metabolism, Royal Victoria Infirmary, Newcastle upon Tyne, UK

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Su Ann Tee,

Su Ann Tee

Department of Endocrinology, Diabetes & Metabolism, Royal Victoria Infirmary, Newcastle upon Tyne, UK

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Yasir Ihsan,

Yasir Ihsan

Department of Endocrinology, Diabetes & Metabolism, Royal Victoria Infirmary, Newcastle upon Tyne, UK

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Waseem Athar,

Waseem Athar

Department of Respiratory Medicine, Royal Victoria Infirmary, Newcastle upon Tyne, UK

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Gabriella Marchitelli,

Gabriella Marchitelli

orcid.org/0000-0003-2442-0547

Department of Acute Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK

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Donna Kelly,

Donna Kelly

Department of Anaesthetics & Critical Care, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK

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Christopher S. Boot,

Christopher S. Boot

Department of Blood Sciences, Royal Victoria Infirmary, Newcastle upon Tyne, UK

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Nadia Stock,

Nadia Stock

Department of Acute Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK

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James Macfarlane,

James Macfarlane

Department of Respiratory Medicine, Royal Victoria Infirmary, Newcastle upon Tyne, UK

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Adrian R. Martineau,

Adrian R. Martineau

Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK

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Graham Burns,

Graham Burns

Department of Respiratory Medicine, Royal Victoria Infirmary, Newcastle upon Tyne, UK

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Richard Quinton,

Corresponding Author

Richard Quinton

[email protected]

orcid.org/0000-0002-4842-8095

Department of Endocrinology, Diabetes & Metabolism, Royal Victoria Infirmary, Newcastle upon Tyne, UK

Translational & Clinical Research Institute, University of Newcastle upon Tyne, UK

Correspondence

Richard Quinton, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK.

Email: [email protected]

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Grigorios Panagiotou,

Grigorios Panagiotou

orcid.org/0000-0003-0690-1478

Department of Endocrinology, Diabetes & Metabolism, Royal Victoria Infirmary, Newcastle upon Tyne, UK

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Su Ann Tee,

Su Ann Tee

Department of Endocrinology, Diabetes & Metabolism, Royal Victoria Infirmary, Newcastle upon Tyne, UK

Search for more papers by this author

Yasir Ihsan,

Yasir Ihsan

Department of Endocrinology, Diabetes & Metabolism, Royal Victoria Infirmary, Newcastle upon Tyne, UK

Search for more papers by this author

Waseem Athar,

Waseem Athar

Department of Respiratory Medicine, Royal Victoria Infirmary, Newcastle upon Tyne, UK

Search for more papers by this author

Gabriella Marchitelli,

Gabriella Marchitelli

orcid.org/0000-0003-2442-0547

Department of Acute Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK

Search for more papers by this author

Donna Kelly,

Donna Kelly

Department of Anaesthetics & Critical Care, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK

Search for more papers by this author

Christopher S. Boot,

Christopher S. Boot

Department of Blood Sciences, Royal Victoria Infirmary, Newcastle upon Tyne, UK

Search for more papers by this author

Nadia Stock,

Nadia Stock

Department of Acute Medicine, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK

Search for more papers by this author

James Macfarlane,

James Macfarlane

Department of Respiratory Medicine, Royal Victoria Infirmary, Newcastle upon Tyne, UK

Search for more papers by this author

Adrian R. Martineau,

Adrian R. Martineau

Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK

Search for more papers by this author

Graham Burns,

Graham Burns

Department of Respiratory Medicine, Royal Victoria Infirmary, Newcastle upon Tyne, UK

Search for more papers by this author

Richard Quinton,

Corresponding Author

Richard Quinton

[email protected]

orcid.org/0000-0002-4842-8095

Department of Endocrinology, Diabetes & Metabolism, Royal Victoria Infirmary, Newcastle upon Tyne, UK

Translational & Clinical Research Institute, University of Newcastle upon Tyne, UK

Correspondence

Richard Quinton, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK.

Email: [email protected]

Search for more papers by this author

First published: 03 July 2020

https://doi.org/10.1111/cen.14276

Citations: 135

Grigorios Panagiotou and Su Ann Tee contributed equally to this work.

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REFERENCES

1Khunti K, Singh AK, Pareek M, Hanif W. Is ethnicity linked to incidence or outcomes of COVID-19? BMJ. 2020; 369: M1548.
10.1136/bmj.m1548
PubMedGoogle Scholar
2Hill TR, Granic A, Davies K, et al. Serum 25-hydroxyvitamin d concentration and its determinants in the very old: the newcastle 85+ study. Osteoporos Int. 2016; 27(3): 1199-1208.
10.1007/s00198-015-3366-9
CASPubMedWeb of Science®Google Scholar
3Pereira-Santos M, Costa PR, Assis AM, Santos CA, Santos DB. obesity and vitamin d deficiency: a systematic review and meta-analysis. Obes Rev. 2015; 16(4): 341-349.
10.1111/obr.12239
CASPubMedWeb of Science®Google Scholar
4Gruber–Bzura BM. Vitamin D and influenza—prevention or therapy? Int J Mol Sci. 2018; 19(8): 2419.
10.3390/ijms19082419
Web of Science®Google Scholar
5Berry DJ, Hesketh K, Power C, Hypponen E. Vitamin D status has a linear association with seasonal infections and lung function in British adults. Br J Nutr. 2011; 106(9): 1433-1440.
10.1017/S0007114511001991
CASPubMedWeb of Science®Google Scholar
6Aspell N, Laird E, Healy M, Shannon T, Lawlor B, O'Sullivan M. The prevalence and determinants of vitamin d status in community-dwelling older adults: results from the english longitudinal study of ageing (ELSA). Nutrients. 2019; 11(6): 1253.
10.3390/nu11061253
CASWeb of Science®Google Scholar
7Romagnoli E, Mascia ML, Cipriani C, et al. Short and long-term variations in serum calciotropic hormones after a single very large dose of ergocalciferol (vitamin d2) or cholecalciferol (vitamin d3) in the elderly. J Clin Endocrinol Metab. 2008; 93(8): 3015-3020.
10.1210/jc.2008-0350
CASPubMedWeb of Science®Google Scholar
8Grant WB, Lahore H, Mcdonnell SL, et al. evidence that vitamin d supplementation could reduce risk of influenza and COVID-19 infections and deaths. Nutrients. 2020; 12(4): 988.
10.3390/nu12040988
CASPubMedWeb of Science®Google Scholar
9Ilie PC, Stefanescu S, Smith L. The role of vitamin d in the prevention of coronavirus disease 2019 infection and mortalitY. Aging Clin Exp Res. 2020. 32: 1195–1198.
10.1007/s40520-020-01570-8
PubMedWeb of Science®Google Scholar
10Lau FH, Majumder R, Torabi R, et al. vitamin d insufficiency is prevalent in severe COVID-19. Medrxiv. 2020; 2020: 2004. 2024.20075838.

Google Scholar
11Hastie CE, Mackay DF, Ho F, et al. Vitamin D concentrations and COVID-19 infection in uk biobank. Diabetes Metab Syndr. 2020; 14(4): 561-565.
10.1016/j.dsx.2020.04.050
PubMedWeb of Science®Google Scholar

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Volume93, Issue4

October 2020

Pages 508-511

Low serum 25-hydroxyvitamin D (25[OH]D) levels in patients hospitalized with COVID-19 are associated with greater disease severity

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Low serum 25-hydroxyvitamin D (25[OH]D) levels in patients hospitalized with COVID-19 are associated with greater disease severity

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