year | antibiotic | class | natural product | synthetic |
1929 (activity) | penicillin | β-lactam | √ | |
1940 (purification) | ||||
1932 | sufapyridine | sulfonamide | √ | |
1944 | streptomycin | aminoglycoside | √ | |
1945 | cephalosporin | β-lactam | √ | |
1947 | chloramphenicol | phenypropanoid | √ | |
1948 | chlortetracycline | tetracycline | √ | |
1950 | erythromycin | macrolide | √ | |
1955 | vancomycin | glycopeptide | √ | |
1955 | virginiamycin | streptogramin | √ | |
1955 | amphotericin | polyene (antifungal) | √ | |
1955 | lincomycin | lincosamide | √ | |
1959 | rifamycin | ansamycin | √ | |
1962 | nalidixic acid | quinolone | √ | |
1969 | fosfomycin | phosphonate | √ | |
2000 | linezolid | oxazolidinone | √ | |
2003 | daptomycin | lipopeptide | √ |
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