Pseudohyperaldosteronism from liquorice-containing laxatives

J Endocrinol Invest. 1990 Nov;13(10):847-8. doi: 10.1007/BF03349639.

Abstract

Four cases of pseudohyperaldosteronism due to chronic ingestion of liquorice-containing laxatives are described. All patients had hypertension and hypokalemia with suppression of plasma renin activity and aldosterone; the diagnosis was based only on retrospective grounds. In patients with hypokalemia and hypertension a possibility of such a cause must be excluded to avoid unnecessary diagnostic procedures.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Aldosterone / blood
  • Cathartics / adverse effects*
  • Drug Combinations
  • Female
  • Glycyrrhiza*
  • Humans
  • Hyperaldosteronism / blood
  • Hyperaldosteronism / chemically induced*
  • Hyperaldosteronism / drug therapy
  • Male
  • Middle Aged
  • Plant Extracts / adverse effects
  • Plant Oils / adverse effects
  • Plants, Medicinal*
  • Potassium / blood
  • Renin / blood
  • Senna Extract / adverse effects
  • Spironolactone / therapeutic use

Substances

  • Cathartics
  • Drug Combinations
  • Midro
  • Plant Extracts
  • Plant Oils
  • liquorice decocta
  • Spironolactone
  • Aldosterone
  • Senna Extract
  • Renin
  • Potassium