Found 91 cases where Vaccine is COVID19 and Symptom is Creutzfeldt-Jakob disease or Variant Creutzfeldt-Jakob disease

Administered by: Unknown       Purchased by: ?
Symptoms: Anxiety, Aphasia, Asthenia, CSF test abnormal, Computerised tomogram head normal, Creutzfeldt-Jakob disease, Delirium, Disturbance in attention, Hypoxic-ischaemic encephalopathy, Loss of personal independence in daily activities, Lumbar puncture abnormal, Magnetic resonance imaging head abnormal, Paranoia
SMQs:, Neuroleptic malignant syndrome (broad), Anticholinergic syndrome (broad), Ischaemic central nervous system vascular conditions (narrow), Dementia (narrow), Psychosis and psychotic disorders (narrow), Guillain-Barre syndrome (broad), Noninfectious encephalitis (broad), Noninfectious encephalopathy/delirium (narrow), Noninfectious meningitis (broad), Hostility/aggression (broad), Conditions associated with central nervous system haemorrhages and cerebrovascular accidents (broad), Depression (excl suicide and self injury) (broad), Hypoglycaemia (broad), Dehydration (broad), Opportunistic infections (broad)

Life Threatening? Yes
Birth Defect? No
Died? No
Permanent Disability? Yes
Recovered? No
Office Visit? Yes
ER Visit? No
ER or Doctor Visit? Yes
Hospitalized? No
Previous Vaccinations:
Other Medications: metoprolol XL 50mg daily, prilosec 20mg bid prn
Current Illness:
Preexisting Conditions: hypertension, prediabetes
Allergies: vancomycin
Diagnostic Lab Data: CT head w/o contrast 5/7/21 negative. MRI brain 5/16/21 showed Bilateral frontal, parietal and temporal lobes cortical reduced diffusion is most suggestive of sporadic Creutzfeldt Jacob disease. The imaging appearance is not felt to be artifactual. The differential diagnosis includes a recent episode of hypoxic ischemic injury, please correlate with clinical history. 6/16/21 LP/CSF RT-QuIC positive
CDC Split Type:

Write-up: 60 yo M who developed delirium and was in ER 5/7/21 for this. Described by son/boss as difficulty focusing x 2-3 weeks, diffuse body weakness, paranoia, anxiety. CT head was neg, pt was discharged home. outpatient MRI brain suggested Creutzfeldt Jakob disease CJD. He was seen by neurology, who confirmed CJD by LP, he is now nonverbal and dependent on all ADL''s, going into hospice

Administered by: Other       Purchased by: ?
Symptoms: Blood test, Brain neoplasm, Computerised tomogram, Creutzfeldt-Jakob disease, Lumbar puncture, Magnetic resonance imaging, Sleep terror
SMQs:, Dementia (narrow), Non-haematological tumours of unspecified malignancy (narrow), Opportunistic infections (broad)

Life Threatening? No
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? Yes
Hospitalized? Yes, ? days
Extended hospital stay? No
Previous Vaccinations:
Other Medications:
Current Illness: Abstains from alcohol; Blood pressure high; Non-smoker
Preexisting Conditions: Comments: Patient had no known allergies, no drug abuse or illicit drug usage. The patient had always been independent, intelligent with outstanding memory.
Allergies:
Diagnostic Lab Data: Test Date: 202107; Test Name: CT scan; Result Unstructured Data: Unknown; Test Date: 202107; Test Name: Blood test; Result Unstructured Data: unknown; Test Date: 202107; Test Name: Lumbar puncture; Result Unstructured Data: unknown; Test Date: 202107; Test Name: Magnetic resonance imaging; Result Unstructured Data: unknown
CDC Split Type: USJNJFOC20210760791

Write-up: CREUTZFELDT-JAKOB DISEASE; TINY TUMOR IN THE FRONT OF BRAIN; AFRAID AT NIGHT TO STAY ALONE; This spontaneous report received from a consumer concerned a 62 year old female. The patient''s weight was 230 pounds, and height was 67 inches. The patient''s concurrent conditions included high blood pressure, non alcoholic, and non smoker. Patient had no known allergies, no drug abuse or illicit drug usage. Patient had always been independent, intelligent with outstanding memory The patient received covid-19 vaccine ad26.cov2.s (suspension for injection, route of admin not reported, batch number and expiration date was unknown) dose was not reported,1 total, administered on 08-MAR-2021 for prophylactic vaccination. The batch number was not reported and has been requested. No concomitant medications were reported. After 3 weeks receiving the vaccine, patient went downhill. On 29-MAR-2021, the patient had, complained of arm being numb and started forgetting things. She started having very bad memory issue, was afraid at night to stay on her own and was agitated and emotional. She also had coordination issues, could not get into the car on her own, could barely stand up from the sitting position and would go side by side when walking. She could not form an understandable sentence so she was taken to the hospital and hospitalized from 31-MAY-2021 to 17-JUN-2021. Then she was taken to Psychiatric unit and sent her home with an appointment to see a neurologist. On 03-JUL-2021, patient was found naked on the kitchen floor, she could not remember anything and nothing made sense. She was taken back to the hospital with the ambulance and later on (unknown date) the hospital transferred her to the another hospital, at the time of reporting patient was hospitalized there. They did computerized tomography scan, Magnetic resonance imaging, lumbar puncture and blood works but did not have any results. During hospitalization they found a tiny tumor in the front of the brain and diagnosed Creutzfeldt-Jakob disease. The hospital also said no dementia and no Alzheimer''s disease. The action taken with covid-19 vaccine ad26.cov2.s was not applicable. The patient had not recovered from tiny tumor in the front of brain, and creutzfeldt-jakob disease, and the outcome of afraid at night to stay alone was not reported. This report was serious (Hospitalization Caused / Prolonged).; Sender''s Comments: V0: 20210760791-covid-19 vaccine ad26.cov2.s-Creutzfeldt-jakob disease and tiny tumor in the front of brain. This event(s) is considered un-assessable. The event(s) has a compatible/suggestive temporal relationship, is unlabeled, and has unknown scientific plausibility. There is no information on any other factors potentially associated with the event(s).

Administered by: School       Purchased by: ?
Symptoms: Condition aggravated, Confusional state, Creutzfeldt-Jakob disease, Death, Extrapyramidal disorder, Feeling abnormal, Headache, Locked-in syndrome, Lumbar puncture abnormal, Memory impairment, Motor dysfunction, Myoclonus, Pyramidal tract syndrome, Speech disorder
SMQs:, Peripheral neuropathy (broad), Neuroleptic malignant syndrome (broad), Anticholinergic syndrome (broad), Dementia (narrow), Akathisia (broad), Dyskinesia (broad), Dystonia (broad), Parkinson-like events (broad), Psychosis and psychotic disorders (broad), Guillain-Barre syndrome (broad), Noninfectious encephalitis (broad), Noninfectious encephalopathy/delirium (broad), Noninfectious meningitis (broad), Depression (excl suicide and self injury) (broad), Hypoglycaemia (broad), Opportunistic infections (broad)

Life Threatening? Yes
Birth Defect? No
Died? Yes
   Date died: 0000-00-00
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? Yes
Hospitalized? Yes, ? days
Extended hospital stay? No
Previous Vaccinations:
Other Medications:
Current Illness: none
Preexisting Conditions: none
Allergies: none
Diagnostic Lab Data: Lumbar pucture, 07/12/2021 result, CJD.
CDC Split Type:

Write-up: After 2nd dose of Pfizer 4/25/21, by 5/6/2021 complaining of severe headache and showing major symptons of something neurologically wrong- extreme memory fog, confusion, headache.Was hospitalized on 5/31 for about 10 days after a 911 call complaining of a headche. Released in a worsened state. Spent 10 days at home, regressing daily. On 06/19/2021 hospitalized again, doing tests eliminating possibilities.Rapidly regressing, unable to speak full sentences, Myoclonus, loss of motor skills, Pyramidal & extrapyramidal symptoms as well as akinetic mutism. After 3 weeks undiagnosed, on 07/12/2021 LP results confirmed positive for CJD. Was released to hospice on 07/19/2021 and death on 07/22/21.

Administered by: Private       Purchased by: ?
Symptoms: Blood test, Cerebrovascular accident, Computerised tomogram, Creutzfeldt-Jakob disease, Death, Diplopia, Dizziness, Electroencephalogram, Endotracheal intubation, Gait disturbance, Gait inability, Insomnia, Intensive care, Lumbar puncture abnormal, Magnetic resonance imaging, Memory impairment, Restless legs syndrome, Seizure, Speech disorder
SMQs:, Torsade de pointes/QT prolongation (broad), Angioedema (broad), Peripheral neuropathy (broad), Systemic lupus erythematosus (broad), Anticholinergic syndrome (broad), Ischaemic central nervous system vascular conditions (narrow), Haemorrhagic central nervous system vascular conditions (narrow), Dementia (narrow), Convulsions (narrow), Embolic and thrombotic events, vessel type unspecified and mixed arterial and venous (narrow), Dystonia (broad), Parkinson-like events (broad), Psychosis and psychotic disorders (broad), Guillain-Barre syndrome (broad), Noninfectious encephalitis (broad), Noninfectious encephalopathy/delirium (broad), Noninfectious meningitis (broad), Depression (excl suicide and self injury) (broad), Vestibular disorders (broad), Ocular motility disorders (broad), Generalised convulsive seizures following immunisation (narrow), Respiratory failure (broad), Hypoglycaemia (broad), Opportunistic infections (broad)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 2021-07-17
   Days after onset: 107
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: LEVOTHYROXINE
Current Illness: NONE
Preexisting Conditions: NONE
Allergies: NONE
Diagnostic Lab Data: NUMEROUS BLOOD WORK, CAT SCANS, MRI , EEG , LUMBER PUNCTURES
CDC Split Type:

Write-up: DEVELOPED RESTLESS LEG SYNDROME, INSOMNIA, DOUBLE VISION, DIZZINESS WITHIN 3 WEEKS OF LAST SHOT. DIAGNOSED WITH A STROKE ON 05/24/21. WITHIN 24 HOURS OF DISCHARGE, SHE COULD NOT WALK PROPERLY AND HAD TO USE A CANE. RE ENTERED THE HOSPITAL ON 06/7/21 TO REHAB CONTINUED TO DECLINE WITH ADVANCED SYMPTOMS OF GAIT DIFFICULTY, MEMORY AND SPEECH PROBLEMS AND STILL INSOMNIA, ULTIMATELY BEGAN TO HAVE SEIZURES AND WAS INTUBATED AND SEDATED ON 06/21/21. TRANSFERRED TO HOSPITAL 9TH FLOOR NEUROLOGICAL ICU ON 06/25/21 AND BEGAN PROCESS OF DIAGNOSIS WITH A LUMBAR PUNCTURE. RECEIVED THE CJD DIAGNOSIS ON 07/14/21 AND SHE PASSED AWAY ON 07/17/21. MY MOTHER WAS COMPLETELY HEALTHY, WENT TO THE DOCTOR EVERY 6 MONTHS WITH GREAT CHECK UPS , WORKED OUT EVERY DAY, AND LOVED LIFE.

Administered by: Public       Purchased by: ?
Symptoms: Autopsy, Creutzfeldt-Jakob disease, Death, Lumbar puncture, Magnetic resonance imaging head, Prostatectomy
SMQs:, Dementia (narrow), Malignancy related therapeutic and diagnostic procedures (narrow), Prostate malignant tumours (broad), Opportunistic infections (broad)

Life Threatening? Yes
Birth Defect? No
Died? Yes
   Date died: 2021-08-27
   Days after onset: 87
Permanent Disability? No
Recovered? No
Office Visit? Yes
ER Visit? No
ER or Doctor Visit? Yes
Hospitalized? Yes, 9 days
Extended hospital stay? No
Previous Vaccinations:
Other Medications: Blood pressure medicine, staten drug, Plavix, Baby aspirin, Vitamin D, low dose of vitamin C
Current Illness: None
Preexisting Conditions: Had open heart surgery double bypass caught early that?s why he was on that medicine. Had his prostate removed in April 2021
Allergies: None
Diagnostic Lab Data: Spinal tap Brain MRI and brain autopsy
CDC Split Type:

Write-up: Died six months later from CJD.

Administered by: Unknown       Purchased by: ?
Symptoms: Creutzfeldt-Jakob disease
SMQs:, Dementia (narrow), Opportunistic infections (broad)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 0000-00-00
Permanent Disability? Yes
Recovered? No
Office Visit? Yes
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications:
Current Illness:
Preexisting Conditions: Comments: List of non-encoded Patient Relevant History: Patient Other Relevant History 1: None
Allergies:
Diagnostic Lab Data:
CDC Split Type: USPFIZER INC202101401363

Write-up: development of Cruetzfeldt-Jakobs Disease; This is a spontaneous report from a contactable consumer. A 67-year-old male patient received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE), dose 2 via unspecified route in right arm on Mar2021 at 10:00 AM at patient age of 67-year-old as single dose for COVID-19 immunisation. The patient was not diagnosed with COVID-19 prior to vaccination. The patient had no known allergies. The patient medical history and concomitant medication was none. The patient did not receive any other vaccines within 4 weeks prior to the COVID vaccine. The patient previously received BNT162B2 (PFIZER-BIONTECH COVID-19 VACCINE), dose 1 via unspecified route in right arm on Mar2021 at 10:00 AM at patient age of 67-year-old as single dose for COVID-19 immunisation. The patient experienced development of Cruetzfeldt-Jakobs Disease in May2021. The event resulted in Doctor or other healthcare professional office/clinic visit, Disability or permanent damage. It was unknown if patient received treatment. The patient has not been tested for COVID-19 post vaccination. The outcome of the event was not recovered. The lot number for the vaccine, [BNT162B2], was not provided and will be requested during follow up.

Administered by: Other       Purchased by: ?
Symptoms: Amnesia, Blood test, Computerised tomogram, Creutzfeldt-Jakob disease, Death, Irritability, Lumbar puncture, Magnetic resonance imaging, Motor dysfunction
SMQs:, Peripheral neuropathy (broad), Dementia (narrow), Akathisia (broad), Dyskinesia (broad), Dystonia (broad), Parkinson-like events (broad), Guillain-Barre syndrome (broad), Noninfectious encephalitis (broad), Noninfectious encephalopathy/delirium (broad), Noninfectious meningitis (broad), Hostility/aggression (broad), Hypoglycaemia (broad), Opportunistic infections (broad)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 2021-10-29
   Days after onset: 211
Permanent Disability? No
Recovered? No
Office Visit? Yes
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications: Lisinopril 10mg
Current Illness: none
Preexisting Conditions: none
Allergies: none
Diagnostic Lab Data: CT scan 9/10/2021 MRI 9/24/21 multiple blood tests and Lumbar Puncture late September 2021
CDC Split Type:

Write-up: what began as memory loss and irritability was followed by loss of motor skills, later diagnosed as Cruetzfeldt-Jakobs disease. Death occurred early morning 10/29/2021.

Administered by: Private       Purchased by: ?
Symptoms: Amnesia, Coordination abnormal, Creutzfeldt-Jakob disease, Lumbar puncture, Magnetic resonance imaging head abnormal, Myoclonus, Tremor
SMQs:, Neuroleptic malignant syndrome (broad), Anticholinergic syndrome (broad), Dementia (narrow), Parkinson-like events (broad), Guillain-Barre syndrome (broad), Noninfectious encephalitis (broad), Noninfectious encephalopathy/delirium (broad), Noninfectious meningitis (broad), Hypoglycaemia (broad), Opportunistic infections (broad)

Life Threatening? Yes
Birth Defect? No
Died? No
Permanent Disability? No
Recovered? No
Office Visit? Yes
ER Visit? No
ER or Doctor Visit? Yes
Hospitalized? Yes, 5 days
Extended hospital stay? No
Previous Vaccinations:
Other Medications: Lisinopril 10mg, aspirin 81mg, balance of nature fruit supplement, balance of nature veggie supplement
Current Illness:
Preexisting Conditions:
Allergies:
Diagnostic Lab Data: Lumbar puncture (02/08/22), RTQuiC (pending, sent 02/08/22), MRI Head with findings consistent with CJD (02/08/22)
CDC Split Type:

Write-up: Patient''s wife states his symptoms of tremors, loss of coordination, startle myoclonus, and memory loss began after receiving the COVID-19 vaccination (symptom onset late 11/2021). COVID-19 booster was given in conjunction with a flu shot but it is currently unknown which type of influenza vaccine and the lot number of said vaccine. He himself is unable to provide reliable history and wife refuses to entertain possibility of symptom onset prior to vaccination, only repeatedly saying there are no symptoms prior to this event. Patient''s symptoms have progressed until hospital admission was necessary. He met all criteria for Probable Creutzfeld-Jakob Disease. He denies ingestion of any wild game, receiving blood transfusions, and being out of the country in the past 10 years. Given the pathophysiology of the disease and the mechanism of the vaccine, it is difficult to draw a correlation between two events outside of coincidence. CJD occurs sporadically in over 90% of cases. Wife is requesting a report be filed given the onset of symptoms after Moderna booster dose.

Administered by: Private       Purchased by: ?
Symptoms: Creutzfeldt-Jakob disease, Death, Dysstasia, Gait inability, Hemiparesis, Tremor
SMQs:, Neuroleptic malignant syndrome (broad), Anticholinergic syndrome (broad), Dementia (narrow), Embolic and thrombotic events, vessel type unspecified and mixed arterial and venous (narrow), Dystonia (broad), Parkinson-like events (broad), Guillain-Barre syndrome (broad), Noninfectious encephalitis (broad), Noninfectious encephalopathy/delirium (broad), Noninfectious meningitis (broad), Conditions associated with central nervous system haemorrhages and cerebrovascular accidents (narrow), Hypoglycaemia (broad), Opportunistic infections (broad)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 2022-02-01
   Days after onset: 129
Permanent Disability? No
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? Yes
Hospitalized? Yes, 14 days
Extended hospital stay? No
Previous Vaccinations:
Other Medications: SSRI, Lisinopril, Multi Vitamins
Current Illness:
Preexisting Conditions: None
Allergies: NoneNone
Diagnostic Lab Data: See Healthcare records from 01/30/2022 through 02/19/2022
CDC Split Type:

Write-up: Shakiness and weakness on left side, inability to stand or walk. Diagnosed as Creutzfeldt - Jacob Disease resulting in death on 02/21/2022

Administered by: Unknown       Purchased by: ?
Symptoms: Creutzfeldt-Jakob disease
SMQs:, Dementia (narrow), Opportunistic infections (broad)

Life Threatening? No
Birth Defect? No
Died? Yes
   Date died: 2021-08-02
Permanent Disability? Yes
Recovered? No
Office Visit? No
ER Visit? No
ER or Doctor Visit? No
Hospitalized? No
Previous Vaccinations:
Other Medications:
Current Illness:
Preexisting Conditions:
Allergies:
Diagnostic Lab Data:
CDC Split Type: USMODERNATX, INC.MOD20225

Write-up: Creutzfeldt-Jakob Disease ,fatal degenerative brain disorder , and her brain degenerated until she passed away on Aug. 2, 2021; This spontaneous case was reported by a consumer and describes the occurrence of CREUTZFELDT-JAKOB DISEASE (Creutzfeldt-Jakob Disease ,fatal degenerative brain disorder , and her brain degenerated until she passed away on Aug. 2, 2021) in a 70-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 vaccination. No Medical History information was reported. On 16-Feb-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 17-Mar-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced CREUTZFELDT-JAKOB DISEASE (Creutzfeldt-Jakob Disease ,fatal degenerative brain disorder , and her brain degenerated until she passed away on Aug. 2, 2021) (seriousness criteria death, disability and medically significant). The patient died on 02-Aug-2021. The reported cause of death was creutzfeldt-jakob disease ,fatal degenerative brain disorder , and her brain degenerated until she passed away on aug. 2, 2021. It is unknown if an autopsy was performed. No concomitant medications reported by reporter. After Moderna vaccination patient felt different and patient developed the symptoms of sporadic Creutzfeldt-Jakob Disease (CJD) included that the Patient developed numbness that spread throughout the entire left side of her body, blindness and hearing loss. Patient lost the ability to walk and communicate, and her brain degenerated until she passed away on 02-Aug-2021. Patient was died just five months after receiving her second dose of Moderna. No treatment medications provided by the reporter. Company Comment: This spontaneous case concerns a 70-year-old female patient with no medical history reported, who experienced the unexpected serious event of Creutzfeldt-Jakob Disease, that occurred on an unknown date after receiving the second dose of mRNA-1273 vaccine (latency between vaccine and event cannot be established), that led to the eventual demise of the patient and assessed as disabling and medically significant. Patient developed numbness that spread throughout the left side of the body and a clinical course of blindness, deafness, loss of ability to walk and communicate, and brain degeneration. Patient reportedly died from the rapid and fatal degenerative brain disorder Creutzfeldt-Jakob Disease 4 months and 16 days post vaccination. However, an autopsy report was not provided. Previously received first dose of COVID-19 vaccine was also mRNA-1273 vaccine (interval between two doses is 29 days). The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report.; Sender''s Comments: This spontaneous case concerns a 70-year-old female patient with no medical history reported, who experienced the unexpected serious event of Creutzfeldt-Jakob Disease, that occurred on an unknown date after receiving the second dose of mRNA-1273 vaccine (latency between vaccine and event cannot be established), that led to the eventual demise of the patient and assessed as disabling and medically significant. Patient developed numbness that spread throughout the left side of the body and a clinical course of blindness, deafness, loss of ability to walk and communicate, and brain degeneration. Patient reportedly died from the rapid and fatal degenerative brain disorder Creutzfeldt-Jakob Disease 4 months and 16 days post vaccination. However, an autopsy report was not provided. Previously received first dose of COVID-19 vaccine was also mRNA-1273 vaccine (interval between two doses is 29 days). The benefit-risk relationship of mRNA-1273 Vaccine is not affected by this report.; Reported Cause(s) of Death: Creutzfeldt-Jakob Disease ,fatal degenerative brain disorder , and her brain degenerated until she passed away on Aug. 2, 2021