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Orginalartikel

Kognitive Langzeitfolgen nach einer akuten Enzephalitiseine

Published Online:August 23, 2011https://doi.org/10.1024/1016-264X/a000044

Abstract

Akute Enzephalitiden sind seltene Erkrankungen. Es existieren nur wenige Untersuchungen bezüglich der kognitiven Langzeiterholung dieser Patienten. Nachfolgende neuropsychologische Studie untersuchte prospektiv kognitive Langzeitfolgen in Patienten nach einer durchgemachten akuten Enzephalitis und verglich sie mit Alters- Geschlechts- und Bildungsgematchten Kontrollpersonen. Die Zeit zwischen Untersuchung und Akutereignis betrug 6 – 93 Monate. Die Ergebnisse zeigten in der Mehrzahl eine positive kognitive Erholung. Im Vordergrund standen unabhängig von der Ätiologie der Enzephalitis Störungen des Antriebs und der Exekutivfunkionen. Eine postenzephalitische Epilepsie erwies sich als negativer Risikofaktor für die kognitive Rehabilitation.


Cognitive Long-Term Outcome After Acute Encephalitis

Acute encephalitis is a rare disease mainly occurring sporadically. Only limited data as to the long-term prognosis in particular for the regeneration of cognition is available. This study investigated prospectively what influence encephalitis has on cognitive parameters. People who matched the patients in age, gender and level of education were used as a control group. The period between the acute illness and the follow-up investigation amounted to 6 to 93 months. The study showed a favourable outcome in most of the patients. Impaired executive and motivation functions were the most common findings independent of the cause of encephalitis. Post-encephalitis epilepsy revealed to have a negative effect on cognitive rehabilitation.

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