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Decompressive Hemicraniectomy and Suboccipital Craniectomy for Acute Ischemic Stroke

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Ischemic Stroke Therapeutics
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Abstract

Case Presentation: A female in her late 40 s presented for bilateral lung transplantation for pulmonary hypertension. She was kept sedated postoperatively per standard protocol to limit stress on her cardiopulmonary function. When sedation was lightened, she was noted to have a left hemiparesis and was stroke alerted. CT head demonstrated hypodensity in the right middle cerebral artery territory. CT Perfusion demonstrated completed right-sided MCA infarct. Given her large volume completed infarct, the patient was not a candidate for mechanical thrombectomy.

Given the significant mass effect already present, after discussion regarding the risks and benefits of surgery with her family, the patient was taken to the operating room for emergent decompressive hemicraniectomy. She experienced a good neurological recovery and was able to follow commands in all extremities by the time of his discharge albeit with a left-sided hemiparesis. With a plan to perform cranioplasty following inpatient rehabilitation.

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References

  1. Jüttler E, Schellinger PD, Aschoff A, Zweckberger K, Unterberg A, Hacke W. Clinical review: therapy for refractory intracranial hypertension in ischaemic stroke. Crit Care. 2007;11(5):231.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Gupta R, Connolly ES, Mayer S, Elkind MS. Hemicraniectomy for massive middle cerebral artery territory infarction: a systematic review. Stroke. 2004;35(2):539–43.

    Article  PubMed  Google Scholar 

  3. Mayer SA. Hemicraniectomy: a second chance on life for patients with space-occupying MCA infarction. Stroke. 2007;38(9):2410–2.

    Article  PubMed  Google Scholar 

  4. Vahedi K, Vicaut E, Mateo J, et al. Sequential-design, multicenter, randomized, controlled trial of early decompressive craniectomy in malignant middle cerebral artery infarction (DECIMAL Trial). Stroke. 2007;38(9):2506–17.

    Article  PubMed  Google Scholar 

  5. Rahme R, Zuccarello M, Kleindorfer D, Adeoye OM, Ringer AJ. Decompressive hemicraniectomy for malignant middle cerebral artery territory infarction: is life worth living? J Neurosurg. 2012;117(4):749–54.

    Article  PubMed  Google Scholar 

  6. Weil AG, Rahme R, Moumdjian R, Bouthillier A, Bojanowski MW. Quality of life following hemicraniectomy for malignant MCA territory infarction. Can J Neurol Sci. 2011;38(3):434–8.

    Article  PubMed  Google Scholar 

  7. Benejam B, Sahuquillo J, Poca MA, et al. Quality of life and neurobehavioral changes in survivors of malignant middle cerebral artery infarction. J Neurol. 2009;256(7):1126–33.

    Article  PubMed  Google Scholar 

  8. Lambert SL, Williams FJ, Oganisyan ZZ, Branch LA, Mader EC Jr. Fetal-type variants of the posterior cerebral artery and concurrent infarction in the major arterial territories of the cerebral hemisphere. J Investig Med High Impact Case Rep. 2016;4(3):2324709616665409.

    PubMed  PubMed Central  Google Scholar 

  9. Liebeskind DS. Collateral circulation. Stroke. 2003;34(9):2279–84.

    Article  PubMed  Google Scholar 

  10. Luo L, Song S, Ezenwukwa CC, Jalali S, Sun B, Sun D. Ion channels and transporters in microglial function in physiology and brain diseases. Neurochem Int. 2020;142:104925.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Liu L, Kearns KN, Eli I, et al. Microglial calcium waves during the hyperacute phase of ischemic stroke. Stroke. 2021;52:274–83.

    Article  CAS  PubMed  Google Scholar 

  12. Saver JL. Time is brain—quantified. Stroke. 2006;37(1):263–6.

    Article  PubMed  Google Scholar 

  13. Go KG. The normal and pathological physiology of brain water. Adv Tech Stand Neurosurg. 1997;23:47–142.

    Article  CAS  PubMed  Google Scholar 

  14. Nehring SM, Tadi P, Tenny S. Cerebral edema. In: StatPearls. Treasure Island, FL: StatPearls Publishing LLC; 2020.

    Google Scholar 

  15. van Beek AH, Claassen JA, Rikkert MG, Jansen RW. Cerebral autoregulation: an overview of current concepts and methodology with special focus on the elderly. J Cereb Blood Flow Metab. 2008;28(6):1071–85.

    Article  PubMed  Google Scholar 

  16. Kimelberg HK. Current concepts of brain edema. Review of laboratory investigations. J Neurosurg. 1995;83(6):1051–9.

    Article  CAS  PubMed  Google Scholar 

  17. Frank JI. Large hemispheric infarction, deterioration, and intracranial pressure. Neurology. 1995;45(7):1286–90.

    Article  CAS  PubMed  Google Scholar 

  18. Berrouschot J, Sterker M, Bettin S, Köster J, Schneider D. Mortality of space-occupying (‘malignant’) middle cerebral artery infarction under conservative intensive care. Intensive Care Med. 1998;24(6):620–3.

    Article  CAS  PubMed  Google Scholar 

  19. Krieger DW, Demchuk AM, Kasner SE, Jauss M, Hantson L. Early clinical and radiological predictors of fatal brain swelling in ischemic stroke. Stroke. 1999;30(2):287–92.

    Article  CAS  PubMed  Google Scholar 

  20. Park J, Hwang JH. Where are we now with decompressive hemicraniectomy for malignant middle cerebral artery infarction? J Cerebrovasc Endovasc Neurosurg. 2013;15(2):61–6.

    Article  PubMed  PubMed Central  Google Scholar 

  21. Hofmeijer J, Kappelle LJ, Algra A, Amelink GJ, van Gijn J, van der Worp HB. Surgical decompression for space-occupying cerebral infarction (the hemicraniectomy after middle cerebral artery infarction with life-threatening edema trial [HAMLET]): a multicentre, open, randomised trial. Lancet Neurol. 2009;8(4):326–33.

    Article  PubMed  Google Scholar 

  22. Slezins J, Keris V, Bricis R, et al. Preliminary results of randomized controlled study on decompressive craniectomy in treatment of malignant middle cerebral artery stroke. Medicina (Kaunas). 2012;48(10):521–4.

    PubMed  Google Scholar 

  23. Shaw CM, Alvord EC Jr, Berry RG. Swelling of the brain following ischemic infarction with arterial occlusion. Arch Neurol. 1959;1:161–77.

    Article  CAS  PubMed  Google Scholar 

  24. Hacke W, Schwab S, Horn M, Spranger M, De Georgia M, von Kummer R. ‘Malignant’ middle cerebral artery territory infarction: clinical course and prognostic signs. Arch Neurol. 1996;53(4):309–15.

    Article  CAS  PubMed  Google Scholar 

  25. Treadwell SD, Thanvi B. Malignant middle cerebral artery (MCA) infarction: pathophysiology, diagnosis and management. Postgrad Med J. 2010;86(1014):235–42.

    Article  PubMed  Google Scholar 

  26. Flechsenhar J, Woitzik J, Zweckberger K, Amiri H, Hacke W, Jüttler E. Hemicraniectomy in the management of space-occupying ischemic stroke. J Clin Neurosci. 2013;20(1):6–12.

    Article  PubMed  Google Scholar 

  27. Qureshi AI, Suarez JI, Yahia AM, et al. Timing of neurologic deterioration in massive middle cerebral artery infarction: a multicenter review. Crit Care Med. 2003;31(1):272–7.

    Article  PubMed  Google Scholar 

  28. Haring HP, Dilitz E, Pallua A, et al. Attenuated corticomedullary contrast: an early cerebral computed tomography sign indicating malignant middle cerebral artery infarction. A case-control study. Stroke. 1999;30(5):1076–82.

    Article  CAS  PubMed  Google Scholar 

  29. Oppenheim C, Samson Y, Manaï R, et al. Prediction of malignant middle cerebral artery infarction by diffusion-weighted imaging. Stroke. 2000;31(9):2175–81.

    Article  CAS  PubMed  Google Scholar 

  30. National Guideline C. National Institute for Health and Care Excellence: clinical guidelines. In: Stroke and transient ischaemic attack in over 16s: diagnosis and initial management. London: National Institute for Health and Care Excellence (UK); 2019.

    Google Scholar 

  31. Vahedi K, Hofmeijer J, Juettler E, et al. Early decompressive surgery in malignant infarction of the middle cerebral artery: a pooled analysis of three randomised controlled trials. Lancet Neurol. 2007;6(3):215–22.

    Article  PubMed  Google Scholar 

  32. Jüttler E, Schwab S, Schmiedek P, et al. Decompressive surgery for the treatment of malignant infarction of the middle cerebral artery (DESTINY): a randomized, controlled trial. Stroke. 2007;38(9):2518–25.

    Article  PubMed  Google Scholar 

  33. Dasenbrock HH, Robertson FC, Vaitkevicius H, et al. Timing of decompressive hemicraniectomy for stroke. Stroke. 2017;48(3):704–11.

    Article  PubMed  Google Scholar 

  34. Cushing H. The establishment of cerebral hernia as a decompressive measure for inaccessible brain tumors; with the description of intermuscular methods of making the bone defect in temporal and occipital regions. Surg Gynecol Obstet. 1905;1:297.

    Google Scholar 

  35. Scarcella G. Encephalomalacia simulating the clinical and radiological aspects of brain tumor; a report of 6 cases. J Neurosurg. 1956;13(4):278–92.

    Article  CAS  PubMed  Google Scholar 

  36. Schwab S, Steiner T, Aschoff A, et al. Early hemicraniectomy in patients with complete middle cerebral artery infarction. Stroke. 1998;29(9):1888–93.

    Article  CAS  PubMed  Google Scholar 

  37. Mori K, Ishimaru S, Maeda M. Unco-parahippocampectomy for direct surgical treatment of downward transtentorial herniation. Acta Neurochir. 1998;140(12):1239–44.

    Article  CAS  PubMed  Google Scholar 

  38. Hutchinson P, Timofeev I, Kirkpatrick P. Surgery for brain edema. Neurosurg Focus. 2007;22(5):E14.

    Article  PubMed  Google Scholar 

  39. Beez T, Munoz-Bendix C, Steiger H-J, Beseoglu K. Decompressive craniectomy for acute ischemic stroke. Crit Care. 2019;23(1):209.

    Article  PubMed  PubMed Central  Google Scholar 

  40. Corliss B, Gooldy T, Vaziri S, Kubilis P, Murad G, Fargen K. Complications after in vivo and ex vivo autologous bone flap storage for cranioplasty: a comparative analysis of the literature. World Neurosurg. 2016;96:510–5.

    Article  PubMed  Google Scholar 

  41. Armstrong RE, Ellis MF. Determinants of 30-day morbidity in adult cranioplasty: an ACS-NSQIP analysis of 697 cases. Plast Reconstr Surg Glob Open. 2019;7(12):e2562.

    Article  PubMed  PubMed Central  Google Scholar 

  42. Alkhaibary A, Alharbi A, Alnefaie N, Oqalaa Almubarak A, Aloraidi A, Khairy S. Cranioplasty: a comprehensive review of the history, materials, surgical aspects, and complications. World Neurosurg. 2020;139:445–52.

    Article  PubMed  Google Scholar 

  43. Koller M, Rafter D, Shok G, Murphy S, Kiaei S, Samadani U. A retrospective descriptive study of cranioplasty failure rates and contributing factors in novel 3D printed calcium phosphate implants compared to traditional materials. 3D Print Med. 2020;6:14.

    Article  PubMed  PubMed Central  Google Scholar 

  44. Walcott BP, Kwon CS, Sheth SA, et al. Predictors of cranioplasty complications in stroke and trauma patients. J Neurosurg. 2013;118(4):757–62.

    Article  PubMed  Google Scholar 

  45. Chang V, Hartzfeld P, Langlois M, Mahmood A, Seyfried D. Outcomes of cranial repair after craniectomy. J Neurosurg. 2010;112(5):1120–4.

    Article  PubMed  Google Scholar 

  46. Carvi YNMN, Höllerhage HG. Early combined cranioplasty and programmable shunt in patients with skull bone defects and CSF-circulation disorders. Neurol Res. 2006;28(2):139–44.

    Article  Google Scholar 

  47. Schuss P, Vatter H, Oszvald A, et al. Bone flap resorption: risk factors for the development of a long-term complication following cranioplasty after decompressive craniectomy. J Neurotrauma. 2013;30(2):91–5.

    Article  PubMed  Google Scholar 

  48. Gooch MR, Gin GE, Kenning TJ, German JW. Complications of cranioplasty following decompressive craniectomy: analysis of 62 cases. Neurosurg Focus. 2009;26(6):E9.

    Article  PubMed  Google Scholar 

  49. Giese H, Meyer J, Unterberg A, Beynon C. Long-term complications and implant survival rates after cranioplastic surgery: a single-center study of 392 patients. Neurosurg Rev. 2021;44:1755.

    Article  PubMed  Google Scholar 

  50. Ewald C, Duenisch P, Walter J, et al. Bone flap necrosis after decompressive hemicraniectomy for malignant middle cerebral artery infarction. Neurocrit Care. 2014;20(1):91–7.

    Article  PubMed  Google Scholar 

  51. Wagner S, Schnippering H, Aschoff A, Koziol JA, Schwab S, Steiner T. Suboptimum hemicraniectomy as a cause of additional cerebral lesions in patients with malignant infarction of the middle cerebral artery. J Neurosurg. 2001;94(5):693–6.

    Article  CAS  PubMed  Google Scholar 

  52. Jüttler E, Köhrmann M, Aschoff A, Huttner HB, Hacke W, Schwab S. Hemicraniectomy for space-occupying supratentorial ischemic stroke. Fut Neurol. 2008;3(3):251–64.

    Article  Google Scholar 

  53. van Swieten JC, Koudstaal PJ, Visser MC, Schouten HJ, van Gijn J. Interobserver agreement for the assessment of handicap in stroke patients. Stroke. 1988;19(5):604–7.

    Article  PubMed  Google Scholar 

  54. Yao Y, Liu W, Yang X, Hu W, Li G. Is decompressive craniectomy for malignant middle cerebral artery territory infarction of any benefit for elderly patients? Surg Neurol. 2005;64(2):165–9; discussion 169.

    Article  PubMed  Google Scholar 

  55. Arac A, Blanchard V, Lee M, Steinberg GK. Assessment of outcome following decompressive craniectomy for malignant middle cerebral artery infarction in patients older than 60 years of age. Neurosurg Focus. 2009;26(6):E3.

    Article  PubMed  Google Scholar 

  56. Zhao J, Su YY, Zhang Y, et al. Decompressive hemicraniectomy in malignant middle cerebral artery infarct: a randomized controlled trial enrolling patients up to 80 years old. Neurocrit Care. 2012;17(2):161–71.

    Article  PubMed  Google Scholar 

  57. Jüttler E, Unterberg A, Woitzik J, et al. Hemicraniectomy in older patients with extensive middle-cerebral-artery stroke. N Engl J Med. 2014;370(12):1091–100.

    Article  PubMed  Google Scholar 

  58. Shah S, Murthy SB, Whitehead WE, Jea A, Nassif LM. Decompressive hemicraniectomy in pediatric patients with malignant middle cerebral artery infarction: case series and review of the literature. World Neurosurg. 2013;80(1–2):126–33.

    Article  PubMed  Google Scholar 

  59. Schneck MJ, Origitano TC. Hemicraniectomy and durotomy for malignant middle cerebral artery infarction. Neurosurg Clin N Am. 2008;19(3):459–68. vi

    Article  PubMed  Google Scholar 

  60. Kilincer C, Simsek O, Hamamcioglu MK, Hicdonmez T, Cobanoglu S. Contralateral subdural effusion after aneurysm surgery and decompressive craniectomy: case report and review of the literature. Clin Neurol Neurosurg. 2005;107(5):412–6.

    Article  PubMed  Google Scholar 

  61. Chen X, Johnston D. Constitutively active G-protein-gated inwardly rectifying K+ channels in dendrites of hippocampal CA1 pyramidal neurons. J Neurosci. 2005;25(15):3787–92.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  62. Lee SC, Wang YC, Huang YC, Tu PH, Lee ST. Decompressive surgery for malignant middle cerebral artery syndrome. J Clin Neurosci. 2013;20(1):49–52.

    Article  PubMed  Google Scholar 

  63. Chen HJ, Lee TC, Wei CP. Treatment of cerebellar infarction by decompressive suboccipital craniectomy. Stroke. 1992;23(7):957–61.

    Article  CAS  PubMed  Google Scholar 

  64. Tsitsopoulos PP, Tobieson L, Enblad P, Marklund N. Surgical treatment of patients with unilateral cerebellar infarcts: clinical outcome and prognostic factors. Acta Neurochir. 2011;153(10):2075–83.

    Article  PubMed  Google Scholar 

  65. Wijdicks EF, Sheth KN, Carter BS, et al. Recommendations for the management of cerebral and cerebellar infarction with swelling: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2014;45(4):1222–38.

    Article  PubMed  Google Scholar 

  66. Powers WJ, Rabinstein AA, Ackerson T, et al. Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. 2019;50(12):e344–418.

    Article  PubMed  Google Scholar 

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Laurent, D., Mohan, A., Lucke-Wold, B., Hoh, B. (2024). Decompressive Hemicraniectomy and Suboccipital Craniectomy for Acute Ischemic Stroke. In: Ovbiagele, B., Kim, A.S. (eds) Ischemic Stroke Therapeutics. Springer, Cham. https://doi.org/10.1007/978-3-031-49963-0_8

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