ACS Publications. Most Trusted. Most Cited. Most Read
My Activity
CONTENT TYPES

Immunostimulant Agents from Andrographis paniculata

Cite this: J. Nat. Prod. 1993, 56, 7, 995–999
Publication Date (Print):July 1, 1993
https://doi.org/10.1021/np50097a002
    ACS Legacy Archive

    Article Views

    1024

    Altmetric

    -

    Citations

    257
    LEARN ABOUT THESE METRICS
    Other access options

    Note: In lieu of an abstract, this is the article's first page.

    Free first page

    Read this article

    To access this article, please review the available access options below.

    Get instant access

    Purchase Access

    Read this article for 48 hours. Check out below using your ACS ID or as a guest.

    Recommended

    Access through Your Institution

    You may have access to this article through your institution.

    Your institution does not have access to this content. You can change your affiliated institution below.

    Cited By

    This article is cited by 257 publications.

    1. Samuel Desjardins, Jean-Christophe Andrez, and Sylvain Canesi . A Stereoselective Oxidative Polycyclization Process Mediated by a Hypervalent Iodine Reagent. Organic Letters 2011, 13 (13) , 3406-3409. https://doi.org/10.1021/ol201149u
    2. Lixia Chen, Huajie Zhu, Rui Wang, Kailan Zhou, Yongkui Jing and Feng Qiu. ent-Labdane Diterpenoid Lactone Stereoisomers from Andrographis paniculata. Journal of Natural Products 2008, 71 (5) , 852-855. https://doi.org/10.1021/np0704452
    3. Swapan Pramanick,, Sukdeb Banerjee,, Basudeb Achari,, Binayak Das,, Ashis K. Sen, Sr.,, Sibabrata Mukhopadhyay,, Alain Neuman, and, Thierry Prangé. Andropanolide and Isoandrographolide, Minor Diterpenoids from Andrographis paniculata:  Structure and X-ray Crystallographic Analysis. Journal of Natural Products 2006, 69 (3) , 403-405. https://doi.org/10.1021/np050211n
    4. Dan Yang,, Qiang Gao,, Bao-Fu Zheng, and, Nian-Yong Zhu. Et2AlCl-Promoted Asymmetric Phenylseleno Group Transfer Radical Cyclization Reactions of Unsaturated β-Hydroxy Esters. The Journal of Organic Chemistry 2004, 69 (25) , 8821-8828. https://doi.org/10.1021/jo048322z
    5. Ricky Emery Kamdem,, Shengmin Sang, and, Chi-Tang Ho. Mechanism of the Superoxide Scavenging Activity of Neoandrographolide − A Natural Product from Andrographis paniculata Nees. Journal of Agricultural and Food Chemistry 2002, 50 (16) , 4662-4665. https://doi.org/10.1021/jf025556f
    6. Dan Yang,, Qiang Gao, and, On-Yi Lee. Lewis Acid Promoted Phenylseleno Group Transfer Tandem Radical Cyclization Reactions. Organic Letters 2002, 4 (7) , 1239-1241. https://doi.org/10.1021/ol025750n
    7. Tran Van Loc, Nguyen The Anh, Tran Thi Phuong Thao, Tran Van Chien. Isolation and anti‐inflammatory evaluation of diterpene lactones from Andrographis paniculata collected in Bac Giang province, Vietnam. Vietnam Journal of Chemistry 2024, 56 https://doi.org/10.1002/vjch.202300281
    8. Nehru Sai Suresh Chalichem, Prathiksha Nabhan, Bharathi Bethapudi, Nikita Agarwal, Sasi Kumar Murugan, Mundkinajeddu Deepak. Assessment of Immunomodulatory Activity of AP-Bio® (KalmCold®), a Standardized Extract of Andrographis paniculata Using in vivo and ex vivo Models. Pharmacognosy Magazine 2024, 16 https://doi.org/10.1177/09731296231222378
    9. Bipindra Pandey, Rishiram Baral, Atisammodavardhana Kaundinnyayana, Sushil Panta. Promising hepatoprotective agents from the natural sources: a study of scientific evidence. Egyptian Liver Journal 2023, 13 (1) https://doi.org/10.1186/s43066-023-00248-w
    10. E.E. ITO, E.K. UTEBOR. ANTI-SCHISTOSOMA EFFICACY OF Occimum gratissimum (SCENT LEAF) AND Andrographis paniculata (KING OF BITTERS) AGAINST Schistosoma haematobium CERCARIA. Scientific African 2023, 21 , e01839. https://doi.org/10.1016/j.sciaf.2023.e01839
    11. Gatien Messire, Raphaël Serreau, Sabine Berteina-Raboin. Antioxidant Effects of Catechins (EGCG), Andrographolide, and Curcuminoids Compounds for Skin Protection, Cosmetics, and Dermatological Uses: An Update. Antioxidants 2023, 12 (7) , 1317. https://doi.org/10.3390/antiox12071317
    12. Tanya Kadiyska, Ivan Tourtourikov, Kristiyan Dabchev, Alexandra Zlatarova, Nikolay Stoynev, Radka Hadjiolova, Demetrios Spandidos, Maria Adamaki, Vassilis Zoumpourlis. Herbs and plants in immunomodulation (Review). International Journal of Functional Nutrition 2023, 4 (1) https://doi.org/10.3892/ijfn.2023.31
    13. Vara Prasad Saka, G. V. Narasimha Kumar, Abanti Goswami, Digvijay Verma, Pankaj Gupta. Camphora Augments Humoral Mediated Immunity and Decreases Delayed type Hypersensitivity in BALB/c Mice. Journal of Natural Remedies 2023, , 157-167. https://doi.org/10.18311/jnr/2023/31420
    14. Amit Tomar. Folk medicinal uses of Andrographis paniculata (Kalmegh) to cure malaria. Journal of Non-Timber Forest Products 2023, 29 (4) , 193-194. https://doi.org/10.54207/bsmps2000-2023-HTGY22
    15. Ajeet Singh, Bikarma Singh, Navneet. Bioactive compounds in cancer care and prevention. 2023, 439-468. https://doi.org/10.1016/B978-0-12-824412-8.00007-2
    16. Nuttacha Eva Onsa, Shashanka K. Prasad, Thanongsak Chaiyaso, Chompunut Lumsangkul, Sarana Rose Sommano. Phenotypic and Chemotypic Relations among Local Andrographis paniculata (Burm. f.) Wall Landrace Collection. Horticulturae 2022, 8 (10) , 978. https://doi.org/10.3390/horticulturae8100978
    17. Xiaoli Yin, Xueqi Zhuang, Weitao Luo, Meiqiu Liao, Lin Huang, Qiqian Cui, Jiayi Huang, Chunxia Yan, Zixiang Jiang, Yuan Liu, Weina Wang. Andrographolide promote the growth and immunity of Litopenaeus vannamei, and protects shrimps against Vibrio alginolyticus by regulating inflammation and apoptosis via a ROS-JNK dependent pathway. Frontiers in Immunology 2022, 13 https://doi.org/10.3389/fimmu.2022.990297
    18. Chunyang Zou, Jinyu Men, Yingjin Qu, Chunfeng Jiang, Yao Wang, Lixia Chen, Lei Yuan. Synthesis and anti-influenza virus activity evaluation of novel andrographolide derivatives. Medicinal Chemistry Research 2022, 56 https://doi.org/10.1007/s00044-022-02959-y
    19. Monu Kumar Shukla, Sachin Kumar Singh, Sadanand Pandey, Piyush Kumar Gupta, Anurag Choudhary, Deepak Kumar Jindal, Kamal Dua, Deepak Kumar. Potential Immunomodulatory Activities of Plant Products. South African Journal of Botany 2022, 149 , 937-943. https://doi.org/10.1016/j.sajb.2022.04.055
    20. Amit Tomar. Medicinal use of Andrographis paniculata (Kalmegh) to cure jaundice. Journal of Non-Timber Forest Products 2022, 29 (2) , 83-85. https://doi.org/10.54207/bsmps2000-2022-2NF663
    21. Pallavi Agrawal, Maya S. Nair. An insight into the pharmacological and analytical potential of Andrographolide. Fundamental & Clinical Pharmacology 2022, 36 (4) , 586-600. https://doi.org/10.1111/fcp.12757
    22. Aekkhaluck Intharuksa, Warunya Arunotayanun, Wipawadee Yooin, Panee Sirisa-ard. A Comprehensive Review of Andrographis paniculata (Burm. f.) Nees and Its Constituents as Potential Lead Compounds for COVID-19 Drug Discovery. Molecules 2022, 27 (14) , 4479. https://doi.org/10.3390/molecules27144479
    23. Venu Sharma, Arem Qayum, Kamal K. Kapoor, Debaraj Mukherjee, Shashank K. Singh, Manoj K. Dhar, Sanjana Kaul. Synthesis of 14-deoxy-benzylidene-8,17-epoxy-diene-andrographolide derivatives and evaluation of their anticancer activities. Journal of the Indian Chemical Society 2022, 99 (6) , 100490. https://doi.org/10.1016/j.jics.2022.100490
    24. Genoveffa Nuzzo, Giuseppina Senese, Carmela Gallo, Federica Albiani, Lucia Romano, Giuliana d’Ippolito, Emiliano Manzo, Angelo Fontana. Antitumor Potential of Immunomodulatory Natural Products. Marine Drugs 2022, 20 (6) , 386. https://doi.org/10.3390/md20060386
    25. SURYA PRATAP GOND, SUDHANSHU SAHU, SUDEER RAWAT, A. RAJENDIRAN, ANJU SINGH. IMMUNOMODULATORY NATURAL PRODUCT: REVIEW. Asian Journal of Pharmaceutical and Clinical Research 2022, , 5-9. https://doi.org/10.22159/ajpcr.2022.v15i5.44374
    26. Sam-ang Supharoek, Watsaka Siriangkhawut, Kate Grudpan, Kraingkrai Ponhong. A Simple and Reliable Dispersive Liquid-Liquid Microextraction with Smartphone-Based Digital Images for Determination of Carbaryl Residues in Andrographis paniculata Herbal Medicines Using Simple Peroxidase Extract from Senna siamea Lam. Bark. Molecules 2022, 27 (10) , 3261. https://doi.org/10.3390/molecules27103261
    27. Pulok K Mukherjee, Thomas Efferth, Bhaskar Das, Amit Kar, Suparna Ghosh, Seha Singha, Pradip Debnath, Nanaocha Sharma, Pardeep Kumar Bhardwaj, Pallab Kanti Haldar. Role of medicinal plants in inhibiting SARS-CoV-2 and in the management of post-COVID-19 complications. Phytomedicine 2022, 98 , 153930. https://doi.org/10.1016/j.phymed.2022.153930
    28. Shoaib Ahmad, Tarique Mahmood, Ranjan Kumar, Paramdeep Bagga, Farogh Ahsan, Arshiya Shamim, Abdullah Ansari, Mohammad Shariq. Comparative evaluation of cardioprotective activity of Gala and Fuji apple juice against isoprenaline-induced cardiotoxicity in rats. Journal of Complementary and Integrative Medicine 2022, 19 (1) , 27-36. https://doi.org/10.1515/jcim-2020-0336
    29. Eldiza Puji Rahmi, Endang Kumolosasi, Juriyati Jalil, Fhataheya Buang, Jamia Azdina Jamal. Extracts of Andrographis paniculata (Burm.f.) Nees Leaves Exert Anti-Gout Effects by Lowering Uric Acid Levels and Reducing Monosodium Urate Crystal-Induced Inflammation. Frontiers in Pharmacology 2022, 12 https://doi.org/10.3389/fphar.2021.787125
    30. Nagendra Singh Chauhan, Manju Rawat Singh, Vikas Sharma, Nisha Yadav, Neelam S. Sangwan, Deependra Singh. Traditional Indian Knowledge of Immunity from Plants. 2022, 251-283. https://doi.org/10.1007/978-981-16-8117-2_9
    31. Meenakshi Gupta, Maryam Sarwat. Protective effects of plant-derived natural products against hepatocellular carcinoma. 2022, 609-627. https://doi.org/10.1016/B978-0-323-90572-5.00009-3
    32. Manjunath B. Joshi, Archana Kamath, Aswathy S. Nair, Pooja Yedehali Thimmappa, Sitaram J. Sriranjini, G.G. Gangadharan, Kapaettu Satyamoorthy. Modulation of neutrophil (dys)function by Ayurvedic herbs and its potential influence on SARS-CoV-2 infection. Journal of Ayurveda and Integrative Medicine 2022, 13 (1) , 100424. https://doi.org/10.1016/j.jaim.2021.03.006
    33. Lizhan Su, Yarou Gao, Mingxin Zhang, Zexin Liu, Qisheng Lin, Lang Gong, Jianying Guo, Lixia Chen, Tongqing An, Jianxin Chen. Andrographolide and Its Derivative Potassium Dehydrographolide Succinate Suppress PRRSV Replication in Primary and Established Cells via Differential Mechanisms of Action. Virologica Sinica 2021, 36 (6) , 1626-1643. https://doi.org/10.1007/s12250-021-00455-y
    34. Sumaporn Kasemsumran, Waraporn Apiwatanapiwat, Krairuek Ngowsuwan, Sunee Jungtheerapanich. Rapid selection of Andrographis paniculata medicinal plant materials based on major bioactive using near-infrared spectroscopy. Chemical Papers 2021, 75 (11) , 5633-5644. https://doi.org/10.1007/s11696-021-01746-0
    35. Hung Duc Pham, Muhammad A.B. Siddik, Ut Van Phan, Hoang Minh Le, Md. Arifur Rahman. Enzymatic tuna hydrolysate supplementation modulates growth, nutrient utilisation and physiological response of pompano (Trachinotus blochii) fed high poultry-by product meal diets. Aquaculture Reports 2021, 21 , 100875. https://doi.org/10.1016/j.aqrep.2021.100875
    36. Hailu Yao, Junli Zhao, Lingjia Zhu, Yudan Xie, Nana Zhao, Ruiqi Yao, Huan Sun, Guang Han. Protective effect of the effective part of Andrographis paniculata (Burm.f.) Nees on PM2.5-induced lung injury in rats by modulating the NF-κB pathway. Journal of Ethnopharmacology 2021, 280 , 114420. https://doi.org/10.1016/j.jep.2021.114420
    37. Mikayel Narimanyan, Kristina Jamalyan, Anna Balyan, Anders Barth, Staffan Palm, Georg Wikman, Alexander Panossian. Early intervention with Kan Jang® to treat upper-respiratory tract infections: A randomized, quadruple-blind study. Journal of Traditional and Complementary Medicine 2021, 11 (6) , 552-562. https://doi.org/10.1016/j.jtcme.2021.06.001
    38. Vaishnavi Chandramouli, Shekhar Kumar Niraj, Krishna G. Nair, Jerrine Joseph, Wilson Aruni. Phytomolecules Repurposed as Covid-19 Inhibitors: Opportunity and Challenges. Current Microbiology 2021, 78 (10) , 3620-3633. https://doi.org/10.1007/s00284-021-02639-x
    39. P. Prakash, R. Meena, L. Stanley Abraham, Swetha Sunkar, K. Govindaraju, Durgasruthi Pully, Antony V. Samrot. Evidence-based traditional Siddha formulations for prophylaxis and management of respiratory symptoms in COVID-19 pandemic-a review. Biocatalysis and Agricultural Biotechnology 2021, 35 , 102056. https://doi.org/10.1016/j.bcab.2021.102056
    40. M. Rajanna, B. Bharathi, B.R. Shivakumar, M. Deepak, D'Souza Prashanth, D. Prabakaran, T. Vijayabhaskar, B. Arun. Immunomodulatory effects of Andrographis paniculata extract in healthy adults – An open-label study. Journal of Ayurveda and Integrative Medicine 2021, 12 (3) , 529-534. https://doi.org/10.1016/j.jaim.2021.06.004
    41. Wiwan Worakunphanich, Montarat Thavorncharoensap, Sitaporn Youngkong, Kunlawat Thadanipon, Ammarin Thakkinstian. Safety of Andrographis paniculata : A systematic review and meta‐analysis. Pharmacoepidemiology and Drug Safety 2021, 30 (6) , 727-739. https://doi.org/10.1002/pds.5190
    42. Sanjiv Kumar Biradar, Chandra Kishore Tyagi. Immunomodulatory activity of Alcoholic extracts of Tinospora cordifolia Stem. Research Journal of Pharmacognosy and Phytochemistry 2021, , 73-77. https://doi.org/10.52711/0975-4385.2021.00012
    43. Zoya Malik, Rabea Parveen, Bushra Parveen, Sultan Zahiruddin, Mohammad Aasif Khan, Asifa Khan, Sheersh Massey, Sayeed Ahmad, Syed Akhtar Husain. Anticancer potential of andrographolide from Andrographis paniculata (Burm.f.) Nees and its mechanisms of action. Journal of Ethnopharmacology 2021, 272 , 113936. https://doi.org/10.1016/j.jep.2021.113936
    44. Wen Luo, Li Jia, Jia-Wen Zhang, Dong-Jie Wang, Qiu Ren, Wei Zhang. Andrographolide Against Lung Cancer-New Pharmacological Insights Based on High-Throughput Metabolomics Analysis Combined with Network Pharmacology. Frontiers in Pharmacology 2021, 12 https://doi.org/10.3389/fphar.2021.596652
    45. Jayaraman Selvaraj, Veeraraghavan Vishnu Priya, Periyasamy Vijayalakshmi, Rajagopal Ponnulakshmi. In silico and in vitro Study on the Inhibition of FtsZ Protein of Staphylococcus aureus by Active Compounds from Andrographis paniculata. Journal of Biologically Active Products from Nature 2021, 11 (2) , 116-128. https://doi.org/10.1080/22311866.2021.1908163
    46. Amit Kumar, Gifty Sawhney, Rakesh Kumar Nagar, Narendra Chauhan, Nidhi Gupta, Anpurna Kaul, Zabeer Ahmed, P.L. Sangwan, P. Satheesh Kumar, Govind Yadav. Evaluation of the immunomodulatory and anti-inflammatory activity of Bakuchiol using RAW 264.7 macrophage cell lines and in animal models stimulated by lipopolysaccharide (LPS). International Immunopharmacology 2021, 91 , 107264. https://doi.org/10.1016/j.intimp.2020.107264
    47. Pukar Khanal, Yadu Nandan Dey, Rajesh Patil, Rupesh Chikhale, Manish M. Wanjari, Shailendra S. Gurav, B. M. Patil, Bhavana Srivastava, Sudesh N. Gaidhani. Combination of system biology to probe the anti-viral activity of andrographolide and its derivative against COVID-19. RSC Advances 2021, 11 (9) , 5065-5079. https://doi.org/10.1039/D0RA10529E
    48. Vinod Kumar Gurjar, Dilipkumar Pal. Natural Compounds Extracted from Medicinal Plants and Their Immunomodulatory Activities. 2021, 197-261. https://doi.org/10.1007/978-3-030-54027-2_6
    49. G. Vinayak, N. Praveen. Variations in Andrographolide Content, Phytochemical Constituents and Antioxidant Activity of Leaves of Andrographis paniculata (L.) Nees Collected from Different Locations of Southern India. Asian Journal of Chemistry 2021, 33 (2) , 399-403. https://doi.org/10.14233/ajchem.2021.23020
    50. Bushra Saad Alsahafi, Sawsan Hassan Mahassni. Leptadenia Pyrotechnica Aqueous Extract Suppresses Innate Immunity and Enhances Adaptive Immunity in Rats. International Journal Of Pharmaceutical And Phytopharmacological Research 2021, 11 (5) , 25-33. https://doi.org/10.51847/jHKvAE8csw
    51. Ramesh Kumar, Chavlesh Kumar, Ritu Paliwal, Debjani Roy Choudhury, Isha Singh, Ashok Kumar, Abha Kumari, Rakesh Singh. Development of Novel Genomic Simple Sequence Repeat (g-SSR) Markers and Their Validation for Genetic Diversity Analyses in Kalmegh [Andrographis paniculata (Burm. F.) Nees]. Plants 2020, 9 (12) , 1734. https://doi.org/10.3390/plants9121734
    52. Anand Thirupathi, Chandra M. Shanmugavadivelu, Sampathkumar Natarajan. Fastidious Anatomization of Biota Procured Compounds on Cancer Drug Discovery. Current Pharmaceutical Biotechnology 2020, 21 (5) , 354-363. https://doi.org/10.2174/1389201020666191128145015
    53. Vinod Kumar Verma, Md. Kamaruz Zaman, Shekhar Verma, Santosh Kumar Verma, Khomendra Kumar Sarwa. Role of semi-purified andrographolide from Andrographis paniculata extract as nano-phytovesicular carrier for enhancing oral absorption and hypoglycemic activity. Chinese Herbal Medicines 2020, 12 (2) , 142-155. https://doi.org/10.1016/j.chmed.2019.12.004
    54. Debalina Das, Maumita Bandyopadhyay. Novel approaches towards over-production of andrographolide in in vitro seedling cultures of Andrographis paniculata. South African Journal of Botany 2020, 128 , 77-86. https://doi.org/10.1016/j.sajb.2019.10.015
    55. Eugenie Mussard, Annabelle Cesaro, Eric Lespessailles, Brigitte Legrain, Sabine Berteina-Raboin, Hechmi Toumi. Andrographolide, A Natural Antioxidant: An Update. Antioxidants 2019, 8 (12) , 571. https://doi.org/10.3390/antiox8120571
    56. Emmanuelle Villedieu-Percheron, Véronique Ferreira, Joana Filomena Campos, Emilie Destandau, Chantal Pichon, Sabine Berteina-Raboin. Quantitative Determination of Andrographolide and Related Compounds in Andrographis paniculata Extracts and Biological Evaluation of Their Anti-Inflammatory Activity. Foods 2019, 8 (12) , 683. https://doi.org/10.3390/foods8120683
    57. Anindya Santra, Sabyasachi Kundagrami. Beneficiary effect of kalmegh-extract for improving seed storage, viability and vigour some economically important crops. International Journal of Chemical and Environmental Sciences 2019, 1 (1) , 49-57. https://doi.org/10.15864/ijcaes.1107
    58. Lin Gan, Yuanru Zheng, Lijuan Deng, Pinghua Sun, Jiaxi Ye, Xiduan Wei, Feifei Liu, Linzhong Yu, Wencai Ye, Chunlin Fan, Junshan Liu, Wenqing Zhang. Diterpenoid Lactones with Anti-Inflammatory Effects from the Aerial Parts of Andrographis paniculata. Molecules 2019, 24 (15) , 2726. https://doi.org/10.3390/molecules24152726
    59. Sai Giridhar Sarma Kandanur, Somanath Kundu, Christian Cadena, Homero San Juan, Avinash Bajaj, Juan David Guzman, Srinivas Nanduri, Nageswara Rao Golakoti. Design, synthesis, and biological evaluation of new 12-substituted-14-deoxy-andrographolide derivatives as apoptosis inducers. Chemical Papers 2019, 73 (7) , 1669-1675. https://doi.org/10.1007/s11696-019-00718-9
    60. Gajendra Nath Maity, Prasenjit Maity, Adhiraj Dasgupta, Krishnendu Acharya, Sudipta Dalai, Soumitra Mondal. Structural and antioxidant studies of a new arabinoxylan from green stem Andrographis paniculata (Kalmegh). Carbohydrate Polymers 2019, 212 , 297-303. https://doi.org/10.1016/j.carbpol.2019.02.051
    61. Bisi O. Adeoye, Ademola A. Oyagbemi, Ebunoluwa R. Asenuga, Temidayo O. Omobowale, Adeolu A. Adedapo. The ethanol leaf extract of Andrographis paniculata blunts acute renal failure in cisplatin-induced injury in rats through inhibition of Kim-1 and upregulation of Nrf2 pathway. Journal of Basic and Clinical Physiology and Pharmacology 2019, 30 (2) , 205-217. https://doi.org/10.1515/jbcpp-2017-0120
    62. Xiaowei Sun, Huijiao Yan, Yujie Zhang, Xiao Wang, Dawei Qin, Jinqian Yu. Preparative Separation of Diterpene Lactones and Flavones from Andrographis paniculate Using Off-Line Two-Dimensional High-Speed Counter-Current Chromatography. Molecules 2019, 24 (3) , 620. https://doi.org/10.3390/molecules24030620
    63. Rabea Parveen, Bushra Parveen, Abida Parveen, Sayeed Ahmad. Andrographis paniculata: From Traditional to Nano Drug for Cancer Therapy. 2019, 317-345. https://doi.org/10.1007/978-3-030-05569-1_13
    64. Arathi Nair, Debprasad Chattopadhyay, Bhaskar Saha. Plant-Derived Immunomodulators. 2019, 435-499. https://doi.org/10.1016/B978-0-12-814619-4.00018-5
    65. Sunil Kumar, Awantika Singh, Vikas Bajpai, Kulwant R. Sharma, Brijesh Kumar. Identification and Characterization of Terpenoid Lactones and Flavonoids from Ethanolic Extract of Andrographis Paniculata (Burm.f.) Nees Using Liquid Chromatography/Tandem Mass Spectrometry. SEPARATION SCIENCE PLUS 2018, 1 (12) , 762-770. https://doi.org/10.1002/sscp.201800106
    66. Masyitah Hamidah, Aty Widyawaruyanti, Widjiati Widjiati, Budi Prasetyo. Sambiloto (AS201-01) is better than standard antimalarial drug (DHP) in reducing Toll-Like Receptor 2 (TLR2) on placenta malaria model. Majalah Obstetri & Ginekologi 2018, 26 (2) , 74. https://doi.org/10.20473/mog.V26I22018.74-82
    67. Venu Sharma, Kamal K. Kapoor, Debaraj Mukherjee, Vivek K. Gupta, Manoj K. Dhar, Sanjana Kaul. Camphor sulphonic acid mediated quantitative 1,3–diol protection of major Labdane diterpenes isolated from Andrographis paniculata. Natural Product Research 2018, 32 (15) , 1751-1759. https://doi.org/10.1080/14786419.2017.1402313
    68. Qin Zhu, Peifen Zheng, Jianying Zhou, Xinyu Chen, Yuliang Feng, Weifeng Wang, Feng Zhou, Qiaona He. Andrographolide affects Th1/Th2/Th17 responses of peripheral blood mononuclear cells from ulcerative colitis patients. Molecular Medicine Reports 2018, 369 https://doi.org/10.3892/mmr.2018.8992
    69. Zhenfang Gao, Cuicui Yu, Haiyue Liang, Xuekai Wang, Yue Liu, Xin Li, Kai Ji, Hui Xu, Mingyan Yang, Ke Liu, Dong Qi, Huaying Fan. Andrographolide derivative CX-10 ameliorates dextran sulphate sodium-induced ulcerative colitis in mice: Involvement of NF-κB and MAPK signalling pathways. International Immunopharmacology 2018, 57 , 82-90. https://doi.org/10.1016/j.intimp.2018.02.012
    70. Bushra Sultana, Sadaf Yaqoob, Zohaib Zafar, Haq Nawaz Bhatti. Escalation of liver malfunctioning: A step toward Herbal Awareness. Journal of Ethnopharmacology 2018, 216 , 104-119. https://doi.org/10.1016/j.jep.2018.01.002
    71. Bolta Ram Meena, , Sunita T. Pandey, . The historical perspective and applications of kalmegh (Andrographis paniculataNees) in traditional and modern medicine. Asian Agri-History 2018, 22 (1) , 1-8. https://doi.org/10.18311/aah/2018/v22i1/18190
    72. Haider Rahman, Marina Kim, Galen Leung, Jesse A. Green, Seymour Katz. Drug-Herb Interactions in the Elderly Patient with IBD: a Growing Concern. Current Treatment Options in Gastroenterology 2017, 15 (4) , 618-636. https://doi.org/10.1007/s11938-017-0154-y
    73. Reshma Kumari, Sumit Kumar, Ashwani Kumar, Kapil Kumar Goel, Ramesh Chandra Dubey. Antibacterial, antioxidant and Immuno-modulatory properties in extracts of Barleria lupulina Lindl.. BMC Complementary and Alternative Medicine 2017, 17 (1) https://doi.org/10.1186/s12906-017-1989-4
    74. Navneeta Bharadvaja. Medicinal Plants in the Management of Cancer: A Review. International Journal of Complementary & Alternative Medicine 2017, 9 (2) https://doi.org/10.15406/ijcam.2017.09.00291
    75. Jyoti Kalola, Rahul Shah, Arti Patel, Suman K. Lahiri, Mamta B. Shah. Anti-inflammatory and immunomodulatory activities of Inula cappa roots (Compositae). Journal of Complementary and Integrative Medicine 2017, 14 (3) https://doi.org/10.1515/jcim-2016-0083
    76. Devesh Tewari, Andrei Mocan, Emil D. Parvanov, Archana N. Sah, Seyed M. Nabavi, Lukasz Huminiecki, Zheng Feei Ma, Yeong Yeh Lee, Jarosław O. Horbańczuk, Atanas G. Atanasov. Ethnopharmacological Approaches for Therapy of Jaundice: Part II. Highly Used Plant Species from Acanthaceae, Euphorbiaceae, Asteraceae, Combretaceae, and Fabaceae Families. Frontiers in Pharmacology 2017, 8 https://doi.org/10.3389/fphar.2017.00519
    77. Xiao-Yang Hu, Ruo-Han Wu, Martin Logue, Clara Blondel, Lily Yuen Wan Lai, Beth Stuart, Andrew Flower, Yu-Tong Fei, Michael Moore, Jonathan Shepherd, Jian-Ping Liu, George Lewith, . Andrographis paniculata (Chuān Xīn Lián) for symptomatic relief of acute respiratory tract infections in adults and children: A systematic review and meta-analysis. PLOS ONE 2017, 12 (8) , e0181780. https://doi.org/10.1371/journal.pone.0181780
    78. Venu Sharma, Tanwi Sharma, Sanjana Kaul, Kamal K. Kapoor, Manoj K. Dhar. Anticancer potential of labdane diterpenoid lactone “andrographolide” and its derivatives: a semi-synthetic approach. Phytochemistry Reviews 2017, 16 (3) , 513-526. https://doi.org/10.1007/s11101-016-9478-9
    79. Gui-Yang WANG, Ting WEN, Fei-Fei LIU, Hai-Yan TIAN, FAN Chun-Lin, Xiao-Jun HUANG, Wen-Cai YE, Ying WANG. Two new diterpenoid lactones isolated from Andrographis paniculata. Chinese Journal of Natural Medicines 2017, 15 (6) , 458-462. https://doi.org/10.1016/S1875-5364(17)30068-7
    80. Tawit Suriyo, Nanthanit Pholphana, Teerapat Ungtrakul, Nuchanart Rangkadilok, Duangchit Panomvana, Apinya Thiantanawat, Wanwisa Pongpun, Jutamaad Satayavivad. Clinical Parameters following Multiple Oral Dose Administration of a Standardized Andrographis paniculata Capsule in Healthy Thai Subjects. Planta Medica 2017, 83 (09) , 778-789. https://doi.org/10.1055/s-0043-104382
    81. Yu Li, Shengnan He, Jishun Tang, Nana Ding, Xiaoyan Chu, Lianping Cheng, Xuedong Ding, Ting Liang, Shibin Feng, Sajid Ur Rahman, Xichun Wang, Jinjie Wu. Andrographolide Inhibits Inflammatory Cytokines Secretion in LPS-Stimulated RAW264.7 Cells through Suppression of NF- κ B/MAPK Signaling Pathway. Evidence-Based Complementary and Alternative Medicine 2017, 2017 , 1-9. https://doi.org/10.1155/2017/8248142
    82. Li‐Jun Yan, Yong‐Chao Wang. Recent Advances in Green Synthesis of 3,3′‐Spirooxindoles via Isatin–based One–pot Multicomponent Cascade Reactions in Aqueous Medium. ChemistrySelect 2016, 1 (21) , 6948-6960. https://doi.org/10.1002/slct.201601534
    83. R Singh, K Prasad, Mohammed Siddiqui, Kamlesh Prasad. Chapter 2 Medicinal Plants in Preventive and Curative Role for Various Ailments. 2016, 63-100. https://doi.org/10.1201/9781315207506-3
    84. Fuben Xu, Huayu Wu, Kun Zhang, Peizhen Lv, Li Zheng, Jinmin Zhao. Pro-neurogenic effects of andrographolide on RSC96 Schwann cells in vitro. Molecular Medicine Reports 2016, 14 (4) , 3573-3580. https://doi.org/10.3892/mmr.2016.5717
    85. R. Singh, K. K. Prasad, Mohammed Wasim Siddiqui, Kamlesh Prasad. Chapter 2 Medicinal Plants in Preventive and Curative Role for Various Ailments. 2016, 63-100. https://doi.org/10.1201/9781315366326-3
    86. Hafiz Muhammad Farhan Rasheed, Fahad Rasheed, Abdul Wahid Qureshi, Qaiser Jabeen. Immunostimulant activities of the aqueous methanolic extract of Leptadenia pyrotechnica , a plant from Cholistan desert. Journal of Ethnopharmacology 2016, 186 , 244-250. https://doi.org/10.1016/j.jep.2016.03.039
    87. Preeti Chandra, Rekha Kannujia, Renu Pandey, Shipra Shukla, Lal Bahadur, Mahesh Pal, Brijesh Kumar. Rapid quantitative analysis of multi-components in Andrographis paniculata using UPLC-QqQLIT-MS/MS: Application to soil sodicity and organic farming. Industrial Crops and Products 2016, 83 , 423-430. https://doi.org/10.1016/j.indcrop.2015.12.091
    88. Lei Yuan, Chunfeng Zhang, Hongxin Sun, Qingyin Liu, Jian Huang, Lei Sheng, Bin Lin, Jinhui Wang, Lixia Chen. The semi-synthesis of novel andrographolide analogues and anti-influenza virus activity evaluation of their derivatives. Bioorganic & Medicinal Chemistry Letters 2016, 26 (3) , 769-773. https://doi.org/10.1016/j.bmcl.2015.12.100
    89. Manne Sumalatha, Aluru Rammohan, Duvvuru Gunasekar, Alexandre Deville, Bernard Bodo. A New Geranylated Chalcone from Andrographis Lobelioides. Natural Product Communications 2016, 11 (1) , 1934578X1601100. https://doi.org/10.1177/1934578X1601100123
    90. Azizul Isha, Nur A’thifah Yusof, Intan Safinar Ismail. Harvesting Age and Time Effect of Andrographis paniculata Leaf on Its Anti-Inflammatory Activity. Journal of Biosciences and Medicines 2016, 04 (12) , 175-188. https://doi.org/10.4236/jbm.2016.412021
    91. Deepti Arha, Sukanya Pandeti, Akansha Mishra, Swayam Prakash Srivastava, Arvind Kumar Srivastava, Tadigoppula Narender, Akhilesh Kumar Tamrakar. Deoxyandrographolide promotes glucose uptake through glucose transporter-4 translocation to plasma membrane in L6 myotubes and exerts antihyperglycemic effect in vivo. European Journal of Pharmacology 2015, 768 , 207-216. https://doi.org/10.1016/j.ejphar.2015.10.055
    92. Chao Zhang, Xingsheng Qiu. Andrographolide radiosensitizes human ovarian cancer SKOV3 xenografts due to an enhanced apoptosis and autophagy. Tumor Biology 2015, 36 (11) , 8359-8365. https://doi.org/10.1007/s13277-015-3578-9
    93. Alexander Panossian, Ean-Jeong Seo, Georg Wikman, Thomas Efferth. Synergy assessment of fixed combinations of Herba Andrographidis and Radix Eleutherococci extracts by transcriptome-wide microarray profiling. Phytomedicine 2015, 22 (11) , 981-992. https://doi.org/10.1016/j.phymed.2015.08.004
    94. Yanmei Zou, Hua Xiong, Huihua Xiong, Tao Lu, Feng Zhu, Zhiyong Luo, Xianglin Yuan, Yihua Wang. A polysaccharide from Andrographis paniculata induces mitochondrial-mediated apoptosis in human hepatoma cell line (HepG2). Tumor Biology 2015, 36 (7) , 5179-5186. https://doi.org/10.1007/s13277-015-3172-1
    95. Adeolu Alex Adedapo, Bisi Olajumoke Adeoye, Margaret Oluwatoyin Sofidiya, Ademola Adetokunbo Oyagbemi. Antioxidant, antinociceptive and anti-inflammatory properties of the aqueous and ethanolic leaf extracts of Andrographis paniculata in some laboratory animals. Journal of Basic and Clinical Physiology and Pharmacology 2015, 26 (4) , 327-334. https://doi.org/10.1515/jbcpp-2014-0051
    96. . Percutaneous Angioplasty of the Right Coronary Artery Originating from the Left Coronary Sinus. Journal of Cardiology & Current Research 2015https://doi.org/10.15406/jccr.2015.02.00074
    97. CHURIYAH, OLIVIA BUNGA PONGTULURAN, ELRADE ROFAANI, TARWADI. Antiviral and Immunostimulant Activities of Andrographis paniculata. HAYATI Journal of Biosciences 2015, 22 (2) , 67-72. https://doi.org/10.4308/hjb.22.2.67
    98. Shruti Shukla, Archana Mehta. Comparative phytochemical analysis and in vivo immunomodulatory activity of various extracts of Stevia rebaudiana leaves in experimental animal model. Frontiers in Life Science 2015, 8 (1) , 55-63. https://doi.org/10.1080/21553769.2014.961615
    99. Ponnam Devendar, Vadithe Lakshma Nayak, Dharmendra Kumar Yadav, Arigari Niranjana Kumar, Jonnala Kotesh Kumar, KVN Satya Srinivas, Balasubramanian Sridhar, Feroz Khan, Kakaraparthi Pandu Sastry, Sistla Ramakrishna. Synthesis and evaluation of anticancer activity of novel andrographolide derivatives. MedChemComm 2015, 6 (5) , 898-904. https://doi.org/10.1039/C4MD00566J
    100. Xiao-Bo Yu, Guang-Lu Liu, Bin Zhu, Kai Hao, Fei Ling, Gao-Xue Wang. In vitro immunocompetence of two compounds isolated from Polygala tenuifolia and development of resistance against grass carp reovirus (GCRV) and Dactylogyrus intermedius in respective host. Fish & Shellfish Immunology 2014, 41 (2) , 541-548. https://doi.org/10.1016/j.fsi.2014.10.004
    Load more citations

    Pair your accounts.

    Export articles to Mendeley

    Get article recommendations from ACS based on references in your Mendeley library.

    Pair your accounts.

    Export articles to Mendeley

    Get article recommendations from ACS based on references in your Mendeley library.

    You’ve supercharged your research process with ACS and Mendeley!

    STEP 1:
    Click to create an ACS ID

    Please note: If you switch to a different device, you may be asked to login again with only your ACS ID.

    Please note: If you switch to a different device, you may be asked to login again with only your ACS ID.

    Please note: If you switch to a different device, you may be asked to login again with only your ACS ID.

    MENDELEY PAIRING EXPIRED
    Your Mendeley pairing has expired. Please reconnect