Abstract
Tetraoxygenated xanthones, cowaxanthones A-E, together with 10 previously reported tetraoxygenated xanthones, were isolated from the crude hexane extract of the fruits of Garcinia cowa. Cowaxanthone B has previously been reported as a synthetic xanthone. Their structures were elucidated by analysis of spectroscopic data, especially by 1D and 2D NMR. The antibacterial activities of the isolated compounds were also evaluated.
Publication types
- Research Support, Non-U.S. Gov't
MeSH terms
- Anti-Bacterial Agents / chemistry*
- Anti-Bacterial Agents / isolation & purification
- Anti-Bacterial Agents / pharmacology
- Fruit / chemistry*
- Garcinia / chemistry*
- Methicillin Resistance
- Nuclear Magnetic Resonance, Biomolecular
- Plant Extracts / chemistry
- Plant Extracts / isolation & purification
- Plant Extracts / pharmacology
- Staphylococcus aureus / drug effects
- Xanthones / chemistry*
- Xanthones / isolation & purification
- Xanthones / pharmacology
Substances
- Anti-Bacterial Agents
- Plant Extracts
- Xanthones