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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1982 1
1985 4
1987 1
1989 2
1990 4
1991 1
1992 3
1993 3
1994 7
1995 5
1996 7
1997 9
1998 20
1999 11
2000 12
2001 17
2002 16
2003 16
2004 25
2005 26
2006 33
2007 49
2008 36
2009 44
2010 41
2011 59
2012 48
2013 59
2014 46
2015 48
2016 56
2017 74
2018 46
2019 65
2020 86
2021 88
2022 75
2023 57
2024 33

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325 results

Results by year

Filters applied: Meta-Analysis, Review, Systematic Review, in the last 5 years, Humans, English. Clear all
Page 1
Plasmodium falciparum proteases as new drug targets with special focus on metalloproteases.
Mahanta PJ, Lhouvum K. Mahanta PJ, et al. Mol Biochem Parasitol. 2024 Jun;258:111617. doi: 10.1016/j.molbiopara.2024.111617. Epub 2024 Mar 29. Mol Biochem Parasitol. 2024. PMID: 38554736 Review.
With the emergence of parasite resistance to existing drugs including the recently discovered artemisinin, ongoing research seeks novel therapeutic avenues within the malaria parasite. ...
With the emergence of parasite resistance to existing drugs including the recently discovered artemisinin, ongoing research seeks nov …
Emergence, transmission dynamics and mechanisms of artemisinin partial resistance in malaria parasites in Africa.
Rosenthal PJ, Asua V, Conrad MD. Rosenthal PJ, et al. Nat Rev Microbiol. 2024 Jun;22(6):373-384. doi: 10.1038/s41579-024-01008-2. Epub 2024 Feb 6. Nat Rev Microbiol. 2024. PMID: 38321292 Review.
Standard treatment for uncomplicated P. falciparum malaria is artemisinin-based combination therapy (ACT), which includes a rapid-acting artemisinin derivative plus a longer-acting partner drug, and standard therapy for severe P. falciparum malaria is intravenous ar …
Standard treatment for uncomplicated P. falciparum malaria is artemisinin-based combination therapy (ACT), which includes a rapid-act …
The prevalence of Pfk13 polymorphism in malaria patients treated with artemisinin-based therapy: a systematic review and meta-analysis.
Hung DT, Tran L, Tam DNH, Elshafei G, Cuong NTK, Ha NX, Khader SAE, Le Quang L, Shaikhkhalil HW, Abdallfatah A, Aziz JMA, Hirayama K, Huy NT. Hung DT, et al. Parasitol Res. 2024 May 14;123(5):209. doi: 10.1007/s00436-024-08203-3. Parasitol Res. 2024. PMID: 38740597
Artemisinin (ART) combination therapy is the main treatment for malaria. ...
Artemisinin (ART) combination therapy is the main treatment for malaria. ...
Repurposing of anti-malarial drugs for the treatment of tuberculosis: realistic strategy or fanciful dead end?
Hanscheid T, Del Portal Luyten CR, Hermans SM, Grobusch MP. Hanscheid T, et al. Malar J. 2024 May 3;23(1):132. doi: 10.1186/s12936-024-04967-2. Malar J. 2024. PMID: 38702649 Free PMC article. Review.
METHODS: This review included studies on the activity of anti-malarial drugs, specifically quinolones and artemisinins, against Mycobacterium tuberculosis complex (MTC), summarizing results from in vitro, in vivo (animal models) studies, and clinical trials. ...RESULTS: Ni …
METHODS: This review included studies on the activity of anti-malarial drugs, specifically quinolones and artemisinins, against Mycob …
Systematic Review and Geospatial Modeling of Molecular Markers of Resistance to Artemisinins and Sulfadoxine-Pyrimethamine in Plasmodium falciparum in India.
Nain M, Dhorda M, Flegg JA, Gupta A, Harrison LE, Singh-Phulgenda S, Otienoburu SD, Harriss E, Bharti PK, Behera B, Rahi M, Guerin PJ, Sharma A. Nain M, et al. Am J Trop Med Hyg. 2024 Apr 2;110(5):910-920. doi: 10.4269/ajtmh.23-0631. Print 2024 May 1. Am J Trop Med Hyg. 2024. PMID: 38574550 Free PMC article.
Another Use for a Proven Drug: Experimental Evidence for the Potential of Artemisinin and Its Derivatives to Treat Alzheimer's Disease.
Kiss E, Kins S, Gorgas K, Venczel Szakács KH, Kirsch J, Kuhse J. Kiss E, et al. Int J Mol Sci. 2024 Apr 9;25(8):4165. doi: 10.3390/ijms25084165. Int J Mol Sci. 2024. PMID: 38673751 Free PMC article. Review.
Plant-derived multitarget compounds may represent a promising therapeutic strategy for multifactorial diseases, such as Alzheimer's disease (AD). Artemisinin and its derivatives were indicated to beneficially modulate various aspects of AD pathology in different AD animal …
Plant-derived multitarget compounds may represent a promising therapeutic strategy for multifactorial diseases, such as Alzheimer's disease …
Does acute malnutrition in young children increase the risk of treatment failure following artemisinin-based combination therapy? A WWARN individual patient data meta-analysis.
WWARN ACT Malaria and Malnutrition Study Group. WWARN ACT Malaria and Malnutrition Study Group. Lancet Glob Health. 2024 Apr;12(4):e631-e640. doi: 10.1016/S2214-109X(24)00003-2. Lancet Glob Health. 2024. PMID: 38485430 Free PMC article.
It remains unknown whether malnutrition affects the efficacy of WHO-recommended artemisinin-based combination therapies (ACTs). A previous systematic review was inconclusive as data were sparse and heterogeneous, indicating that other methodological approaches, such as ind …
It remains unknown whether malnutrition affects the efficacy of WHO-recommended artemisinin-based combination therapies (ACTs). A pre …
Phytochemicals targeting Alzheimer's disease via the AMP-activated protein kinase pathway, effects, and mechanisms of action.
Zhao Z, Yan J, Huang L, Yang X. Zhao Z, et al. Biomed Pharmacother. 2024 Apr;173:116373. doi: 10.1016/j.biopha.2024.116373. Epub 2024 Mar 4. Biomed Pharmacother. 2024. PMID: 38442672 Free article. Review.
Additionally, several AMPK-related pathways are involved in the anti-AD mechanism, including the AMPK/CaMKKbeta/mTOR, AMPK/SIRT1/PGC-1alpha, AMPK/NF-kappaB/NLRP3, AMPK/mTOR, and PERK/eIF2alpha pathways. Notably, urolithin A, artemisinin, justicidin A, berberine, stigmaster …
Additionally, several AMPK-related pathways are involved in the anti-AD mechanism, including the AMPK/CaMKKbeta/mTOR, AMPK/SIRT1/PGC-1alpha, …
Brazilian plants with antimalarial activity: A review of the period from 2011 to 2022.
Viana Dos Santos MB, Braga de Oliveira A, Veras Mourão RH. Viana Dos Santos MB, et al. J Ethnopharmacol. 2024 Mar 25;322:117595. doi: 10.1016/j.jep.2023.117595. Epub 2023 Dec 18. J Ethnopharmacol. 2024. PMID: 38122914 Review.
The main drugs used in the treatment of human malaria, quinine and artemisinin, are isolates of medicinal plants, making the use of plants a widespread practice in countries where malaria is endemic. Over the years, due to the increased resistance of the parasite to chloro …
The main drugs used in the treatment of human malaria, quinine and artemisinin, are isolates of medicinal plants, making the use of p …
325 results