Abstract
The integrated processing of signals transduced by activating and inhibitory cell surface receptors regulates NK cell effector functions. Here, I review the structure, function, and ligand specificity of the receptors responsible for NK cell recognition.
Publication types
- Research Support, N.I.H., Extramural
- Research Support, U.S. Gov't, P.H.S.
- Review
MeSH terms
- Animals
- Histocompatibility Antigens Class I / metabolism
- Humans
- Immunity, Innate
- Killer Cells, Natural / immunology*
- Ligands
- Mice
- Models, Immunological
- Receptors, Immunologic / chemistry
- Receptors, Immunologic / genetics
- Receptors, Immunologic / metabolism
- Signal Transduction
Substances
- Histocompatibility Antigens Class I
- Ligands
- Receptors, Immunologic