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Neural Stimulation with a Carbon Nanotube Microelectrode Array

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Department of Applied Physics, Department of Ophthalmology, Department of Chemistry, and Department of Electrical Engineering, Stanford University, Stanford, California 94305
Cite this: Nano Lett. 2006, 6, 9, 2043–2048
Publication Date (Web):August 26, 2006
https://doi.org/10.1021/nl061241t
Copyright © 2006 American Chemical Society
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    Abstract

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    We present a novel prototype neural interface using vertically aligned multiwalled carbon nanotube (CNT) pillars as microelectrodes. Functionalized hydrophilic CNT microelectrodes offer a high charge injection limit (1−1.6 mC/cm2) without faradic reactions. The first repeated in vitro stimulation of hippocampal neurons with CNT electrodes is demonstrated. These results suggest that CNTs are capable of providing far safer and more efficacious solutions for neural prostheses than previous metal electrode approaches.

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    *

     Corresponding author, [email protected].

    †

     Department of Applied Physics.

    ‡

     Department of Ophthalmology.

    §

     Present address:  Plager Vision Center, Santa Cruz, CA.

    ‖

     Department of Chemistry.

    ⊥

     Department of Electrical Engineering.

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    EIS Bode plots of CNT electrodes before and after surface treatments, potential transient demonstrating the durability of CNT electrodes under continuous pulsing, and an image of a CNT microelectrode array with a bonded chamber. This material is available free of charge via the Internet at http://pubs.acs.org.

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    58. Saba Moslehi, Conor Rowland, Julian H. Smith, William J. Watterson, David Miller, Cristopher M. Niell, Benjamín J. Alemán, Maria-Thereza Perez, Richard P. Taylor, . Controlled assembly of retinal cells on fractal and Euclidean electrodes. PLOS ONE 2022, 17 (4) , e0265685. https://doi.org/10.1371/journal.pone.0265685
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    78. Zuoxian Xiang, Chuanxiang Tang, Chao Chang, Guozhi Liu. A new viewpoint and model of neural signal generation and transmission: Signal transmission on unmyelinated neurons. Nano Research 2021, 14 (3) , 590-600. https://doi.org/10.1007/s12274-020-3016-1
    79. Anindya Nag, Md Eshrat E. Alahi, Subhas Chandra Mukhopadhyay. Recent progress in the fabrication of graphene fibers and their composites for applications of monitoring human activities. Applied Materials Today 2021, 22 , 100953. https://doi.org/10.1016/j.apmt.2021.100953
    80. Sahar Elyahoodayan, Wenxuan Jiang, Curtis D. Lee, Xiecheng Shao, Gregory Weiland, John J. Whalen, Artin Petrossians, Dong Song. Stimulation and Recording of the Hippocampus Using the Same Pt-Ir Coated Microelectrodes. Frontiers in Neuroscience 2021, 15 https://doi.org/10.3389/fnins.2021.616063
    81. Myriam Barrejón Araque, Susanna Bosi. Carbon Nanomaterials for Neuronal Tissue Engineering. 2021, 184-222. https://doi.org/10.1039/9781839161070-00184
    82. Mohaddeseh Vafaiee, Raheleh Mohammadpour, Manouchehr Vossoughi, Elham Asadian, Mahyar Janahmadi, Pezhman Sasanpour. Carbon Nanotube Modified Microelectrode Array for Neural Interface. Frontiers in Bioengineering and Biotechnology 2021, 8 https://doi.org/10.3389/fbioe.2020.582713
    83. Yoonkey Nam. State-of-the-Art Technology on MEAs for Interfacing Live Neurons. 2021, 1-41. https://doi.org/10.1007/978-981-15-2848-4_8-2
    84. Daniel R. Merrill. Electrodes and instrumentation for neurostimulation. 2021, 77-150. https://doi.org/10.1016/B978-0-12-822828-9.00002-2
    85. Elisa Castagnola, X. Sally Zheng, X. Tracy Cui. Flexible and Soft Materials and Devices for Neural Interface. 2021, 1-61. https://doi.org/10.1007/978-981-15-2848-4_5-1
    86. Stephanie N. Iwasa, HaoTian H. Shi, Sung Hwa Hong, Tianhao Chen, Melissa Marquez-Chin, Christian Iorio-Morin, Suneil K. Kalia, Milos R. Popovic, Hani E. Naguib, Cindi M. Morshead. Novel Electrode Designs for Neurostimulation in Regenerative Medicine: Activation of Stem Cells. Bioelectricity 2020, 2 (4) , 348-361. https://doi.org/10.1089/bioe.2020.0034
    87. Anastasia Ludwig, Sebnem Kesaf, Joonas J. Heikkinen, Tatiana Sukhanova, Shokoufeh Khakipoor, Florence Molinari, Christophe Pellegrino, Sung I. Kim, Jeon G. Han, Henri J. Huttunen, Sari E. Lauri, Sami Franssila, Ville Jokinen, Claudio Rivera. Novel carbon film induces precocious calcium oscillation to promote neuronal cell maturation. Scientific Reports 2020, 10 (1) https://doi.org/10.1038/s41598-020-74535-6
    88. Maryam A. Hejazi, Wei Tong, Alastair Stacey, Shi H. Sun, Molis Yunzab, Ali Almasi, Young Jun Jung, Hamish Meffin, Kate Fox, Khatereh Edalati, Athavan Nadarajah, Steven Prawer, Michael R. Ibbotson, David. J Garrett. High Fidelity Bidirectional Neural Interfacing with Carbon Fiber Microelectrodes Coated with Boron‐Doped Carbon Nanowalls: An Acute Study. Advanced Functional Materials 2020, 30 (52) https://doi.org/10.1002/adfm.202006101
    89. Valentin Saunier, Emmanuel Flahaut, Marie-Charline Blatché, Christian Bergaud, Ali Maziz. Carbon nanofiber-PEDOT composite films as novel microelectrode for neural interfaces and biosensing. Biosensors and Bioelectronics 2020, 165 , 112413. https://doi.org/10.1016/j.bios.2020.112413
    90. Dong-Hyun Baek, Seungjoon Ahn, Ho Seob Kim, Dae Wook Kim. Fabrication of Donut-Type Neural Electrode for Visual Information as Well as Surface Electrical Stimulation. Journal of Medical and Biological Engineering 2020, 40 (5) , 630-638. https://doi.org/10.1007/s40846-020-00540-9
    91. Korkut Terkan, Francisco Zurita, Touba Jamal Khalaf, Philipp Rinklin, Tetsuhiko Teshima, Tobias Kohl, Bernhard Wolfrum. Soft peripheral nerve interface made from carbon nanotubes embedded in silicone. APL Materials 2020, 8 (10) https://doi.org/10.1063/5.0021887
    92. Zaid Aqrawe, Nitish Patel, Yukti Vyas, Mahima Bansal, Johanna Montgomery, Jadranka Travas-Sejdic, Darren Svirskis, . A simultaneous optical and electrical in-vitro neuronal recording system to evaluate microelectrode performance. PLOS ONE 2020, 15 (8) , e0237709. https://doi.org/10.1371/journal.pone.0237709
    93. S. I. Dorovskikh, D. D. Klyamer, T. P. Koretskaya, D. B. Kal′nyi, N. B. Morozova. STUDYING THE MICROSTRUCTURE OF Pt LAYERS PREPARED BY CHEMICAL VAPOR DEPOSITION IN THE PRESENCE OF HYDROGEN. Journal of Structural Chemistry 2020, 61 (8) , 1211-1218. https://doi.org/10.1134/S0022476620080053
    94. Saeid Aslnejad, Morteza Nasiri, Farhang Abbasi, Hamed Abdipour. Preparation of MWCNT/PDMS Conductive Micro-Patterned Nanocomposites. Macromolecular Research 2020, 28 (8) , 733-738. https://doi.org/10.1007/s13233-020-8095-z
    95. Luigi Pavone, Slavianka Moyanova, Federica Mastroiacovo, Laura Fazi, Carla Busceti, Anderson Gaglione, Katiuscia Martinello, Sergio Fucile, Domenico Bucci, Anna Prioriello, Ferdinando Nicoletti, Francesco Fornai, Piero Morales, Roberto Senesi. Chronic neural interfacing with cerebral cortex using single-walled carbon nanotube-polymer grids. Journal of Neural Engineering 2020, 17 (3) , 036032. https://doi.org/10.1088/1741-2552/ab98db
    96. William J. Watterson, Saba Moslehi, Conor Rowland, Kara M. Zappitelli, Julian H. Smith, David Miller, Julie E. Chouinard, Stephen L. Golledge, Richard P. Taylor, Maria-Thereza Perez, Benjamín J. Alemán. The Roles of an Aluminum Underlayer in the Biocompatibility and Mechanical Integrity of Vertically Aligned Carbon Nanotubes for Interfacing with Retinal Neurons. Micromachines 2020, 11 (6) , 546. https://doi.org/10.3390/mi11060546
    97. Mulaine Shih, Chia-Tung Kuo, Min-Hsuan Lin, Yung-Jen Chuang, Hsin Chen, Tri-Rung Yew. A 3D-CNT micro-electrode array for zebrafish ECG study including directionality measurement and drug test. Biocybernetics and Biomedical Engineering 2020, 40 (2) , 701-708. https://doi.org/10.1016/j.bbe.2020.02.008
    98. Xuefei Shen, Yu Zhao, Qian Li, Tao Chen. Construction and electrochemical properties determination of carbon nanotubes/porous-network carbon micron tubes/silk fibroin composite film neural electrode. AIP Advances 2020, 10 (4) https://doi.org/10.1063/5.0003595
    99. Pengju Li, Hashina Parveen Anwar Ali, Wen Cheng, Jingyi Yang, Benjamin C. K. Tee. Bioinspired Prosthetic Interfaces. Advanced Materials Technologies 2020, 5 (3) https://doi.org/10.1002/admt.201900856
    100. Manping Jia, Marco Rolandi. Soft and Ion‐Conducting Materials in Bioelectronics: From Conducting Polymers to Hydrogels. Advanced Healthcare Materials 2020, 9 (5) https://doi.org/10.1002/adhm.201901372
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