Levothyroxine

Drug Usage Statistics, United States, 2013 - 2021

Levothyroxine Summary for 2021

Top drug rank	#3 ( 1)
Estimated number of prescriptions in the United States (2021)	89,309,050
Estimated number of patients in the United States (2021)	19,064,382

Average total drug cost (USD)
Per prescription	$23.92
Per day of therapy	$0.45/day
Average out-of-pocket cost (USD)
Per prescription	$12.01
Per day of therapy	$0.24/day

Total Prescriptions and Patients Per Year (2013 - 2021)

Rank of Top Drugs Over Time

"Rank" refers to the frequency that a given medication is prescribed within a calendar year compared to all other medications. A rank of "4" would indicate that the medication was the fourth most commonly prescribed medication.

Year	Rank	Change
2013	2	1
2014	2	0
2015	1	1
2016	1	0

Year	Rank	Change
2017	3	2
2018	2	1
2019	2	0
2020	2	0
2021	3	1

Drug Cost Over Time (2013 - 2021)

Cost Per Prescription Fill: Average cost per filled prescription regardless of how many days of therapy the prescription is filled for (e.g. 10 days, 30 days, 90 days, etc.)
Cost per Day of Therapy: The average cost per prescription fill divided by the days of therapy. For example, a 10-day antibiotic course costing $30 would be $3 per day. Similarly, a 30-day supply of an oral antihypetensive costing $30 would be $1 per day.

Total cost: The average total cost of the medication including the out-of-pocket cost (see below) plus the amount paid by other parties (Medicare, Medicaid, private insurance, Veterans Administration, TRICARE, other state/federal sources, Worker's compensation, and other miscellaneous sources)
Out-of-pocket cost: The average payment made by the patient which may include deductibles, coinsurance, copayments, or the cash price paid without insurance coverage.

Cost Per Prescription Fill (USD)

Cost Per Day of Therapy (USD/day)

Distribution of Dispensed Dosage Forms (2021)

Dosage Form	Strength	% of Dispensed Products
Tablet/capsule	50 mcg	17.8%
Tablet/capsule	75 mcg	17.4%
Tablet/capsule	100 mcg	11.7%
Tablet/capsule	25 mcg	9.7%
Tablet/capsule	125 mcg	9.6%
Tablet/capsule	88 mcg	8.6%
Tablet/capsule	112 mcg	8.5%
Tablet/capsule	150 mcg	6.7%
Other, unspecified, or misc.		10.0%

Distribution of Days Supplied (2021)

"Days supply" is defined as the number of days that a prescription should last. For example, a prescription of 60 tablets that is taken twice daily has a day supply of 30 days.

Related Drugs

Drug Name	Total Prescriptions (2021)
Levothyroxine (this drug)	89,309,051

Therapeutic Classes

Drug Synonyms

Drug synonyms are used during the sanitation and standardization process of "cleaning" the original data source (MEPS). Occassionally, brand names may be listed below that are no longer on the market or are very infrequently used.

Brand Name Synonyms

Levo-t
Levolet
Levothroid
Levoxyl
Novothyrox
Synthroid
Tirosint
Unithroid
Thyro-tabs
Tirosint-sol
Euthyrox
Thyquidity
Levothyroxine Sodium
Ermeza

Generic Drug Synonyms and Salts

Levothyroxine Sodium
Levothyroxine Sodium Anhydrous
Levothyroxine

FDA Approval Information

Established Pharmacologic Class (EPC):	l-Thyroxine
Initial FDA approval date:	8/21/2000
First FDA applicant:	Rx
First dosage form:	Tablet (oral)

Prescription data source: Medical Expenditure Panel Survey (MEPS) 2013-2021. Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. ClinCalc DrugStats Database version 2024.01. Read more about the ClinCalc DrugStats database.

All ClinCalc DrugStats figures and graphs on this page are licensed under Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0).

Search

Follow Us!

Get Email Updates

New and Popular

Open Menu

Cite This Page

Show AMA citation

Gorillas can't learn drug therapy ... but you can. The Top 250 Drugs by ClinCalc Academy

Disclaimer - Privacy Policy - Contact Us
Updated Sep 12, 2021

Top