Abstract
This review covers the biosynthesis of the starter units of terpenoids, isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) via the nonmevalonate pathway together with a new enzyme involved in the conversion of IPP and DMAPP, i.e type 2 IPP isomerase. The biosynthesis of terpenoids produced by actinomycetes is also reviewed. 117 references are cited.
MeSH terms
- Actinomyces / metabolism*
- Butadienes / chemistry
- Butadienes / metabolism*
- Carbon-Carbon Double Bond Isomerases / metabolism*
- Hemiterpenes*
- Mevalonic Acid / chemistry
- Mevalonic Acid / metabolism
- Organophosphorus Compounds / chemistry
- Organophosphorus Compounds / metabolism*
- Pentanes*
- Terpenes / chemistry
- Terpenes / metabolism*
Substances
- Butadienes
- Hemiterpenes
- Organophosphorus Compounds
- Pentanes
- Terpenes
- isoprene
- isopentenyl pyrophosphate
- Carbon-Carbon Double Bond Isomerases
- isopentenyldiphosphate delta-isomerase
- Mevalonic Acid