Abstract
An evaluation of antimetastatic properties of succus Aloës was carried out using three types of experimental tumors of mice and rats. It was found that succus Aloës treatment contributes to reduction of tumor mass, metastatic foci and metastasis frequency at different stages of tumor progress without affecting major tumor growth. Succus Aloës potentiates the antitumor effect of 5-fluorouracil and cyclophosphamide as components of combination chemotherapy.
Publication types
- Comparative Study
- English Abstract
MeSH terms
- Aloe*
- Animals
- Antineoplastic Agents*
- Antineoplastic Combined Chemotherapy Protocols
- Carcinoma / drug therapy
- Cyclophosphamide / administration & dosage
- Drug Synergism
- Female
- Fluorouracil / administration & dosage
- Lung Neoplasms / drug therapy
- Lymphoma, Non-Hodgkin / drug therapy
- Male
- Melanoma, Experimental / drug therapy
- Mice
- Mice, Inbred C57BL
- Mice, Inbred CBA
- Neoplasm Metastasis / prevention & control*
- Plants, Medicinal*
- Rats
Substances
- Antineoplastic Agents
- Cyclophosphamide
- Fluorouracil