Evidence that coronavirus superspreading is fat-tailed

Proc Natl Acad Sci U S A. 2020 Nov 24;117(47):29416-29418. doi: 10.1073/pnas.2018490117. Epub 2020 Nov 2.

Abstract

Superspreaders, infected individuals who result in an outsized number of secondary cases, are believed to underlie a significant fraction of total SARS-CoV-2 transmission. Here, we combine empirical observations of SARS-CoV and SARS-CoV-2 transmission and extreme value statistics to show that the distribution of secondary cases is consistent with being fat-tailed, implying that large superspreading events are extremal, yet probable, occurrences. We integrate these results with interaction-based network models of disease transmission and show that superspreading, when it is fat-tailed, leads to pronounced transmission by increasing dispersion. Our findings indicate that large superspreading events should be the targets of interventions that minimize tail exposure.

Keywords: COVID-19; SARS-CoV-2; extreme value theory; infectious disease; superspreading.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Basic Reproduction Number / statistics & numerical data*
  • COVID-19 / epidemiology*
  • COVID-19 / transmission
  • Humans
  • Models, Statistical
  • Pandemics / statistics & numerical data