The Lancet

An “impending calamity” that lacks resonance and action. This is how authors of a new report have described the antimicrobial resistance (AMR) issue. 📄 Two years ago, The Lancet published a study estimating AMR was directly responsible for 1.27 million deaths in 2019, mostly in low- and middle-income countries. While dozens of countries around the world have established national plans on AMR, funds and action are lacking. “AMR is not yet a subject that resonates with the average member of the public and this, in turn, influences how much time politicians are willing to invest in the issue”, says Scott Weeze, Professor at the University of Guelph and member of the Global Leaders Group (GLG) on Antimicrobial Resistance. 🗣️ Some fault communication. “The language we are using is not connecting with people”, argues Professor Otto Cars, Uppsala University, Sweden. He continues: “Instead of focusing on terms like ‘AMR’ or the names of bacteria and antibiotics, we should be talking about the diseases that are going to become untreatable—most people know what pneumonia is.” With concerning projections—by 2035, the cost to health care of treating antibiotic-resistant infections could reach US$412 billion per year—motivating public and political engagement is paramount. There are hopes that the new report and September’s second UN General Assembly high-level meeting on AMR will do just that. Read more from Talha Burki ▶️ https://hubs.li/Q02v14rb0 Image credit: putilich from Getty Images via Canva

Misinformation is not a new phenomenon – far from it. However, the COVID-19 pandemic highlighted how infodemics (an overabundance of information, including mis- and disinformation) pose a threat to health and confidence in research. Two new papers—one in The Lancet Public Health, the other in The Lancet Infectious Diseases—hone in on: 1️⃣ Addressing infodemics through the preventive lens of public health 2️⃣ The social histories of misinformation and infodemics across four pandemic case studies “The spread of health misinformation has always been a public health challenge that has necessitated innovative solutions from medical and public health communities”, write Sabrina L Jin and colleagues. Find links to both papers in the comments section👇 Figure: Public health prevention framework for managing information ecosystems

Many people with breast cancer are being ‘systematically left behind’ due to inaction on inequities and hidden suffering, says a new Lancet Commission. Explore authors’ recommendations to address these urgent challenges in #BreastCancer ▶️ https://hubs.li/Q02sWLSz0

In recent decades, advances in breast cancer research and treatment have led to a 40% fall in breast cancer deaths in some high-income countries. However, the burden of breast cancer still looms large worldwide. Join us tomorrow as we launch a new Lancet Commission, with recommendations to address key challenges in breast cancer. Register now ⬇ bit.ly/3x2EDaE

Cell Press and The Lancet invite you to a free virtual panel examining #neurodiversity within the scientific community. Through a series of engaging presentations and a live Q&A, this event will feature insights from leading experts. Panelists Mary Doherty (University College Dublin), Hari Srinivasan (Vanderbilt University) and Axelle Ahanhanzo (LAUDACE) will offer insights into making spaces safer for neurodivergent people, discuss intersectionality and neurodivergence, and unpack the importance of evolving scientific language to reflect lived experiences while ensuring rigorous scientific investigation. Gain a deeper understanding of the value of neurodiversity in propelling scientific progress. Register today: https://lnkd.in/eMyh9dZe #science #innovation #research

🆕 Prostate cancer cases are projected to double to 2.9 million per year by 2040. In a new Commission report, authors outline evidence-based interventions—such as improved early detection and education programmes—to help save lives and prevent related ill health in the years to come. “As more and more men around the world live to middle and old age, there will be an inevitable rise in the number of prostate cancer cases [...] we need to start planning and take action now”, says Prof. Nick James, co-author. Find out more: https://hubs.li/Q02s4q0Y0 👇 Figure 1: Overview of prostate cancer staging and biology

“The use of starvation as a weapon of war is a crime that must be prosecuted and punished to protect the most basic right of all: human dignity.” The Lancet’s latest Editorial, timed to #WorldHealthDay ▶️ hubs.li/Q02s0Fgk0

Air pollution exposure and cardiometabolic risk – what does the evidence suggest? A recent Global Burden of Disease study estimated that a fifth of worldwide type 2 diabetes is attributable to chronic fine particulate matter (PM2.5) exposure. "Air pollution is by far the most dominant environmental risk factor for health in general, and is responsible for over 9 million annual deaths globally", write authors of a new Review in The Lancet Diabetes & Endocrinology. With 99% of the world's population residing in areas where air pollution levels are above current WHO air quality guidelines, there is a compelling need to better understand the connection between air pollution and cardiometabolic disease, and pathways to address this preventable risk factor. Explore an up-to-date summary of evidence alongside policy interventions ▶️ https://hubs.li/Q02rSYWr0 👇 Figure: Mechanisms of PM2.5-mediated metabolic and cardiovascular effects

Health and human rights—their relationship is close, and both have come under threat in the last two decades. Seventy-five years after the United Nations’ historic ratification of the Universal Declaration of Human Rights, a new International AIDS Society-Lancet Commission outlines recommendations aimed at reversing concerning trends. In the Commission report, eight domains are explored: 1⃣ Pandemics 2⃣ Climate change 3⃣ Displacement 4⃣ Systemic discrimination 5⃣ Sexual and reproductive health 6⃣ Mis- and disinformation 7⃣ Artificial intelligence 8⃣ Economic and commercial determinants of health “The health and human rights paradigm is uncertain [...] We have articulated the legal, policy, and programmatic changes needed,” say authors. 📄 Access all findings and recommendations: https://hubs.li/Q02qHV3-0 👇 Figure: A socioecological model for health and human rights

Save the date for a new Lancet Commission launch 📅 Recent advancements in breast cancer research and treatment have led to a decrease in related deaths of more than 40% in some high-income countries. However, the burden of breast cancer still looms large worldwide. Gross inequities, coupled with the hidden costs of breast cancer, mean that many women and some men are being left behind and forgotten. This is a global blunder. On April 16, hear authors, special guests, and Lancet editors discuss key findings and recommendations from the Commission report. ⬇ Register: bit.ly/3x2EDaE